Actively Recruiting
A Prospective Exploratory Clinical Study of Metronomic Capecitabine as Adjuvant Therapy in Locoregionally Advanced Hypopharyngeal Carcinoma
Led by Eye & ENT Hospital of Fudan University · Updated on 2023-07-11
74
Participants Needed
1
Research Sites
208 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
To explore whether the adjuvant therapy of metronomic capecitabine could improve the disease-free survival of locoregionally advanced hypopharyngeal carcinoma (stage IV：T4N0-1M0，anyTN2-3M0).
CONDITIONS
Official Title
A Prospective Exploratory Clinical Study of Metronomic Capecitabine as Adjuvant Therapy in Locoregionally Advanced Hypopharyngeal Carcinoma
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age between 18 and 65 years old
- Histologically confirmed stage IV hypopharyngeal carcinoma (T4N0-1M0 or any TN2-3M0) per 8th AJCC edition
- Completed standard treatment with curative chemoradiotherapy or radical surgery plus postoperative chemo/radiotherapy
- No clinical signs of remaining locoregional disease or distant metastases after treatment
- Within 8 weeks of completing last radiation dose
- Performance status of ECOG grade 0 or 1
- Adequate blood counts, liver, and kidney function as defined
- Provided written informed consent for the study
You will not qualify if you...
- Known intolerance or allergy to capecitabine
- Prior malignancy except treated basal cell or squamous cell skin cancer or in situ cervical cancer
- Severe ongoing illness posing high risk or affecting study compliance (e.g., unstable cardiac disease, renal disease, chronic hepatitis, poorly controlled diabetes)
- Presence of esophagus cancer
- Pregnancy or breastfeeding
- Other conditions making the patient ineligible for the study
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Eye & ENT Hospital, Fudan University
Shanghai, China
Actively Recruiting
Research Team
L
Lei Tao
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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