Actively Recruiting

Age: 7Years +
All Genders
Healthy Volunteers
NCT02994121

Prospective Investigation of Multiple Sclerosis in the Three Rivers Region

Led by University of Pittsburgh · Updated on 2025-12-29

7500

Participants Needed

1

Research Sites

1569 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

In this longitudinal prospective natural history study of multiple sclerosis (MS), the overarching goal is to understand the factors that influence individual variation in disease trajectory and treatment response and pave the way for realizing precision medicine in MS. Because MS is a chronic neurological disorder, this observational cohort study will span a 30-year time frame.

CONDITIONS

Official Title

Prospective Investigation of Multiple Sclerosis in the Three Rivers Region

Who Can Participate

Age: 7Years +
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Age 7 years or older
  • Willing and able to provide consent if 18 years or older, or assent with permission from at least one parent if under 18 years
  • Diagnosis of multiple sclerosis or related disorders, including a first central nervous system demyelinating episode with positive MRI, or abnormal MRI scans characteristic of MS without clinical symptoms
  • For healthy controls: age 7 years or older
  • For healthy controls: no known personal history of multiple sclerosis or related disorders
  • For healthy controls: no other chronic diseases
  • Healthy controls can be family members, unrelated household controls, or from the general population
Not Eligible

You will not qualify if you...

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AI-Screening

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Trial Site Locations

Total: 1 location

1

University of Pittsburgh

Pittsburgh, Pennsylvania, United States, 15260

Actively Recruiting

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Research Team

Z

Zongqi Xia, MD, PhD

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

2

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