Completed

Phase 3
Age: 18Years - 75Years
All Genders
ID00000566

Led by National Heart, Lung, and Blood Institute (NHLBI) · Updated on 2016-04-15

N/A

Participants Needed

N/A

Research Sites

N/A

Total Duration

On this page

AI-Summary

What this Trial Is About

To evaluate the sensitivity and specificity of two major, widely used technologies, radionuclear imaging (ventilation-perfusion scanning) and pulmonary angiography, for the diagnosis of pulmonary embolism.

CONDITIONS

Official Title

Prospective Investigation of Pulmonary Embolism Diagnosis (PIOPED)

Who Can Participate

Age: 18Years - 75Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

Men and women suspected of having a pulmonary embolism and who met the criteria to undergo angiography.

Not Eligible

You will not qualify if you...

History of severe allergic reactions to study medication Currently pregnant or breastfeeding Recent participation in another clinical trial within the last 30 days Presence of uncontrolled medical conditions that could affect safety

Trial Site Locations

Site Locations not provided

Location information for this trial is currently unavailable.

How is the study designed?

Study Type

INTERVENTIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

DIAGNOSTIC

Number of Arms

0

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Published Research Related To This Trial

Can pulmonary angiography be limited to the most suspicious side if the contralateral side appears normal on the ventilation/perfusion lung scan? Data from PIOPED. Prospective Investigation of Pulmonary Embolism Diagnosis.

A Gottschalk, P D Stein, J W Henry...

https://pubmed.ncbi.nlm.nih.gov/8697839

Value of the ventilation/perfusion scan in acute pulmonary embolism. Results of the prospective investigation of pulmonary embolism diagnosis (PIOPED).

PIOPED Investigators

https://pubmed.ncbi.nlm.nih.gov/2332918

Usefulness of noninvasive diagnostic tools for diagnosis of acute pulmonary embolism in patients with a normal chest radiograph.

P D Stein, A Alavi, A Gottschalk...

https://pubmed.ncbi.nlm.nih.gov/2024602

Diagnostic utility of ventilation/perfusion lung scans in acute pulmonary embolism is not diminished by pre-existing cardiac or pulmonary disease.

P D Stein, R E Coleman, A Gottschalk...

https://pubmed.ncbi.nlm.nih.gov/1889240

Clinical, laboratory, roentgenographic, and electrocardiographic findings in patients with acute pulmonary embolism and no pre-existing cardiac or pulmonary disease.

P D Stein, M L Terrin, C A Hales...

https://pubmed.ncbi.nlm.nih.gov/1909617