Actively Recruiting
Prospective IR-led Sedation Feasibility
Led by CAMC Health System · Updated on 2026-03-09
40
Participants Needed
1
Research Sites
56 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This study wants to see if some interventional radiology (IR) procedures can be done without using general anesthesia. General anesthesia needs a lot of staff and equipment. It can also cause side effects. There are not enough anesthesia providers, which makes it harder to use for every procedure. The researchers will test deep sedation with ketamine instead. They will start with 20 patients. If it works well and is safe, they may include up to 40 patients. Patients will be asked to join the study before their procedure. The anesthesia team will be told ahead of time and will be ready to help if needed. The IR team will give the deep sedation and follow all safety rules. The main goal is to finish the procedure without stopping early or switching to general anesthesia. The study will call this successful if fewer than 10% of cases fail. The researchers will also look at patient pain, patient satisfaction, any side effects, and how long recovery takes.
CONDITIONS
Official Title
Prospective IR-led Sedation Feasibility
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age 18 and older
- Planned to undergo an image-guided interventional radiology procedure normally requiring general anesthesia
- Determined appropriate for IR-led ketamine deep sedation by the performing IR physician with anesthesiology available
- Ability to provide written informed consent for deep sedation study participation
You will not qualify if you...
- Eaten solid food within 6-8 hours before the procedure
- Known allergy or hypersensitivity to ketamine, fentanyl, or midazolam
- Unable to provide informed consent or lack decision-making capacity
- Prisoner status
- Uncontrolled hypertension or conditions where ketamine's effects pose unacceptable risk (such as aortic dissection or acute myocardial infarction)
- Pregnancy or breastfeeding
- History of schizophrenia or other psychotic disorders contraindicating ketamine
- Medical conditions judged unsafe for ketamine sedation by the IR physician and anesthesiology
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
CAMC Memorial
Charleston, West Virginia, United States, 25304
Actively Recruiting
Research Team
A
Amy R Deipolyi, M.D., Ph.D.
CONTACT
A
Adam M Belcher, Ph.D.
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
TREATMENT
Number of Arms
1
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here