Actively Recruiting
Prospective Longitudinal Monocentric Study to Measure Limb Movement in Patients With FGFR3-related Skeletal Dysplasia
Led by SYSNAV · Updated on 2026-02-20
40
Participants Needed
1
Research Sites
103 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The study aims to identify which Syde®-derived digital outcomes are reliable in FGFR3-related Skeletal Dysplasia. This requires to set-up a natural history study to measure limb movements in patients with ACH or HCH.
CONDITIONS
Official Title
Prospective Longitudinal Monocentric Study to Measure Limb Movement in Patients With FGFR3-related Skeletal Dysplasia
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Aged 3 years or older at the time of consent
- Written informed consent obtained from parent(s)/legal guardian(s) for participants under 18 years or from participants 18 years and older
- Affiliated to or beneficiary of a social security category
- Able to walk unassisted for at least 10 meters
- Genetically confirmed diagnosis with one pathogenic variant (ACMG class IV & V) of achondroplasia or hypochondroplasia
- Willing and able to comply with all study procedures including questionnaires and Syde�ae related procedures
You will not qualify if you...
- Short stature condition other than achondroplasia or hypochondroplasia
- Cognitive disorders limiting understanding of data collection, device use training, or consent
- Any disease or condition that may interfere with participation, affect growth, motor, balance, or gait functions (e.g., neurological, endocrine, infectious, allergic, osteoarthritis, or inflammatory conditions)
- Females who are pregnant or planning pregnancy during the study
- Body Mass Index equal to or greater than 35 kg/m2
- Recent upper or lower limb injury (trauma, fracture, or surgery) within 6 months before inclusion
- Prior, planned, or expected limb lengthening surgery during the study
- Presence of guided growth hardware or planned orthopedic surgeries during the study
- Vulnerable patients unable to provide informed consent or express consent due to guardianship or similar status
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Hopital Necker
Paris, France, 75015
Actively Recruiting
Research Team
F
Ferial Toumi
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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