Actively Recruiting
Prospective, Longitudinal, Observational Registry of Adult Patients With Hypophosphatasia (REG-HYPO)
Led by Assistance Publique - Hôpitaux de Paris · Updated on 2025-12-16
130
Participants Needed
11
Research Sites
414 weeks
Total Duration
On this page
Sponsors
A
Assistance Publique - Hôpitaux de Paris
Lead Sponsor
U
URC-CIC Paris Descartes Necker Cochin
Collaborating Sponsor
AI-Summary
What this Trial Is About
The purpose of this study is to assess medical events during follow-up of adult patients having hypophosphatasia and consulting rheumatologists.
CONDITIONS
Official Title
Prospective, Longitudinal, Observational Registry of Adult Patients With Hypophosphatasia (REG-HYPO)
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Men and women aged 18 years and older with no upper age limit
- Total alkaline phosphatase value less than 40 IU/l on at least 3 occasions, or total alkaline phosphatase below 40 IU/L with evidence of ALPL gene polymorphism
- Presence of at least one rheumatological symptom
You will not qualify if you...
- Transient hypophosphatasia: no confirmation of alkaline phosphatase below 40 IU/l on at least 3 samples and lack of genetic confirmation
- Secondary hypophosphatasia caused by drugs, endocrine disease, or other genetic diseases as determined by expert rheumatologist
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 11 locations
1
CHU de Bordeaux- Hôpital Pellegrin Place Amélia Raba Léon - 12è étage - Rhumatologie -
Bordeaux, France, France, 33076
Not Yet Recruiting
2
CHU Lille
Lille, France, 59000
Actively Recruiting
3
Hospices Civils de Lyon
Lyon, France, 69003
Not Yet Recruiting
4
CHU Nice
Nice, France
Actively Recruiting
5
Lariboisière Hospital
Paris, France, 75010
Actively Recruiting
6
Cochin Hospital
Paris, France, 75014
Actively Recruiting
7
CHU Poitiers
Poitiers, France, 86000
Actively Recruiting
8
CHU Rennes
Rennes, France, 35000
Actively Recruiting
9
CHU Saint-Etienne
Saint-Priest-en-Jarez, France, 42270
Actively Recruiting
10
Les hôpitaux universitaires de Strasbourg
Strasbourg, France, 67200
Actively Recruiting
11
CHU de Toulouse
Toulouse, France, 31059
Actively Recruiting
Research Team
C
Christian ROUX, MD, PhD
CONTACT
V
Valérie PLENCE, MSc
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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