Actively Recruiting

Age: 1Year - 85Years
All Genders
Healthy Volunteers
NCT04240522

Prospective Longitudinal Observational Research in Atopic Dermatitis

Led by University of Zurich · Updated on 2026-02-05

1000

Participants Needed

1

Research Sites

729 weeks

Total Duration

On this page

Sponsors

U

University of Zurich

Lead Sponsor

U

University of Bonn

Collaborating Sponsor

AI-Summary

What this Trial Is About

Atopic dermatitis (AD) is a frequent chronic relapsing inflammatory skin disorder, characterized by intensely itchy eczema. AD usually starts within the first 2 years of life. In 30 - 60% of children, inflammation spreads onto other body surfaces such as the gastrointestinal tract, the respiratory tract, and the conjunctives within a few years. This sequence is called atopic march. Atopic dermatitis and associated atopic diseases are more frequent in families, suggesting a genetic predisposition. However, the underlying factors such as genetic phenotype, environmental factors, or life style which cause or worsen an existing allergic disease are not understood yet. Affected people suffer from recurrent flares that result in significantly impaired quality. This study will collect clinical and laboratory data to elucidate immunotolerance and preventiv stategies with the aim to develop new and individual treatment options of atopic diseases.

CONDITIONS

Official Title

Prospective Longitudinal Observational Research in Atopic Dermatitis

Who Can Participate

Age: 1Year - 85Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Age 0 to 85 years
  • Diagnosis of atopic dermatitis or another atopic disease such as allergic rhinitis, allergic asthma, or food allergy
  • Inclusion is independent of current therapy; participants will continue medically indicated treatment
  • For healthy controls: age 0 to 85 years with no diagnosis or history of allergic disease
  • Written consent obtained after detailed study information
Not Eligible

You will not qualify if you...

  • Unable to give consent or refusal to participate in the study

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Allergy Unit, Dept. of Dermatology, Unviersity Hosptial of Zurich

Zurich, Canton of Zurich, Switzerland, 8091

Actively Recruiting

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How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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