Actively Recruiting

Age: 18Years +
All Genders
NCT06422546

A Prospective, Multicenter, Non-interventional, Real-world Study to Characterize Changes in Molecular Markers After Three Weeks of Targeted Therapy With Oxitinib in EGFRm NSCLC

Led by Beijing Cancer Prevention & Treatment Society · Updated on 2024-05-21

950

Participants Needed

1

Research Sites

178 weeks

Total Duration

On this page

Sponsors

B

Beijing Cancer Prevention & Treatment Society

Lead Sponsor

C

Cancer Institute and Hospital, Chinese Academy of Medical Sciences

Collaborating Sponsor

AI-Summary

What this Trial Is About

To evaluate the characteristics of genetic variationmutations at baseline and 3 weeks after oxitinib treatment in EGFRm NSCLC

CONDITIONS

Official Title

A Prospective, Multicenter, Non-interventional, Real-world Study to Characterize Changes in Molecular Markers After Three Weeks of Targeted Therapy With Oxitinib in EGFRm NSCLC

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • 18 years or older male or female
  • Stage IV metastatic or recurrent non-squamous NSCLC newly diagnosed, histologically confirmed, and not suitable for radical surgery or radiotherapy (AJCC V8)
  • No prior systemic antitumor therapy including EGFR-TKI or immunotherapy
  • EGFR positive in blood or tissue tested in a local laboratory
  • Able to provide sufficient blood samples for molecular detection
  • Signed informed consent forms available
Not Eligible

You will not qualify if you...

  • Unable to collect plasma samples at baseline
  • EGFR mutant status at baseline not verified by central laboratory
  • Refused subsequent treatment with oxitinib
  • Investigator believes participation may affect study conduct or judgment of results

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Beijing Cancer Prevention society

Beijing, Beijing Municipality, China, 100021

Actively Recruiting

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How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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A Prospective, Multicenter, Non-interventional, Real-world Study to Characterize Changes in Molecular Markers After Three Weeks of Targeted Therapy With Oxitinib in EGFRm NSCLC | DecenTrialz