Actively Recruiting
A Prospective, Multicenter, Single-arm MAC-PD Cohort: a NTM-NET and ESGMYC Collaborative Study
Led by Radboud University Medical Center · Updated on 2025-06-26
100
Participants Needed
11
Research Sites
156 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
To gain insight in the effectiveness of, adherence and adjustments to guideline-based three-drug antimycobacterial therapy in patients with Mycobacterium avium complex pulmonary disease (MAC-PD) during the first 6 months of treatment.
CONDITIONS
Official Title
A Prospective, Multicenter, Single-arm MAC-PD Cohort: a NTM-NET and ESGMYC Collaborative Study
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Newly diagnosed MAC-PD (primary or recurrent) as per the international NTM guideline that requires three-drug antimycobacterial treatment
- Signed and dated informed consent
You will not qualify if you...
- Poor general condition preventing study participation as determined by the Investigator
- Known or suspected current drug or alcohol abuse compromising safety or cooperation
- HIV infection
- Cystic fibrosis
- More than 1 month of antibiotic treatment for current MAC infection
- Less than 6 months between prior antimycobacterial NTM-PD treatment and current treatment
- Disseminated MAC infection
- Active pulmonary tuberculosis, fungal or nocardial disease requiring treatment
- Active pulmonary malignancy or other malignancy requiring chemotherapy or radiotherapy within 6 months before screening or expected during study
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 11 locations
1
Oregon Science and Health University
Portland, Oregon, United States, 97239
Actively Recruiting
2
UZ Leuven
Leuven, Belgium
Actively Recruiting
3
University of Calgary
Calgary, Alberta, Canada
Actively Recruiting
4
University Hospital Center Zagreb
Zagreb, Croatia
Actively Recruiting
5
Aarhus University Hospital
Aarhus, Denmark
Actively Recruiting
6
Rasmus Rude Laub
Hellerup, Denmark
Actively Recruiting
7
University Hospital Frankfurt
Frankfurt, Germany
Actively Recruiting
8
Fukujuji Hospital
Tokyo, Japan
Actively Recruiting
9
Radboud University Medical Center
Nijmegen, Netherlands, 6511LK
Actively Recruiting
10
Seoul National University Hospital
Seoul, South Korea
Actively Recruiting
11
Hospital Clínic de Barcelona
Barcelona, Spain
Actively Recruiting
Research Team
A
Arthur Lemson, MSc
CONTACT
W
Wouter Hoefsloot, MSc, PhD
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here