Actively Recruiting
Prospective Observational Study On The Impact Of Nebilet In Blood Pressure Control In Hypertensive Patients (HYIMPACT)
Led by A.Menarini Asia-Pacific Holdings Pte Ltd · Updated on 2025-04-22
4537
Participants Needed
49
Research Sites
271 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The HYIMPACT study (IMPACT of Nebilet® in Blood Pressure Control in Patients with Hypertension) is a multinational, multicenter, observational, prospective, longitudinal real-world evidence study designed to assess the effectiveness and safety of Nebilet® (nebivolol) in hypertensive patients. The study aims to evaluate changes in systolic and diastolic blood pressure from baseline to 12, 24, and 36 months, as well as treatment adherence, quality of life, prescription patterns, and cardiovascular outcomes. A total of approximately 5,000 hypertensive patients with or without cardiovascular comorbidities will be enrolled across seven Asian countries (Malaysia, Indonesia, the Philippines, Korea, Vietnam, Thailand, and Taiwan). Patients newly initiated on Nebilet®-based treatment or already receiving Nebilet® for no more than two weeks prior to screening will be eligible for inclusion. Patients will be followed at regular intervals for up to three years. The study will also assess the correlation between home and office blood pressure measurements and compare Nebilet® monotherapy with combination therapy in achieving target blood pressure control. The findings from this study will provide real-world insights into the clinical management of hypertension with Nebilet® and its impact on patient outcomes.
CONDITIONS
Official Title
Prospective Observational Study On The Impact Of Nebilet In Blood Pressure Control In Hypertensive Patients (HYIMPACT)
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Adults aged 18 years or older with newly diagnosed or uncontrolled hypertension (office systolic blood pressure �3E= 140 mmHg and/or diastolic blood pressure �3E= 90 mmHg at screening)
- Hypertensive patients with or without cardiovascular conditions such as coronary artery disease, heart failure, peripheral artery disease, cerebrovascular disease, arrhythmias, or valvular heart disease
- Patients newly prescribed Nebilet-based treatment or on Nebilet for no more than 2 weeks at screening
- Willingness to provide consent to participate
- Women of childbearing age willing to use effective contraception
You will not qualify if you...
- Recent major cardiovascular event within the last 3 months
- Heart failure classified as New York Heart Association Class IV
- Contraindications to Nebilet treatment that may risk patient safety or affect study participation as judged by the treating physician
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 49 locations
1
Telogorejo Hospital
Semarang, Central Java, Indonesia, 50134
Actively Recruiting
2
Bethesda Hospital
Yogyakarta, Central Java, Indonesia, 55223
Actively Recruiting
3
Panti rapih Hospital
Yogyakarta, Central Java, Indonesia, 55223
Actively Recruiting
4
Husada Utama Hospital
Surabaya, East Java, Indonesia, 60131
Actively Recruiting
5
Premere Surabaya Hospital
Surabaya, East Java, Indonesia, 60131
Actively Recruiting
6
National Cardiovascular Center Harapan Kita Hospital
Jakarta, Jakarta Special Capital Region, Indonesia, 11420
Actively Recruiting
7
Metropolitan Medical Centre Hospital
Jakarta, Jakarta Special Capital Region, Indonesia, 12940
Actively Recruiting
8
Bidakara Medical Centre
Selatan, Jakarta Special Capital Region, Indonesia, 12870
Actively Recruiting
9
PT Ekamas International Hospital
Pekanbaru, Riau, Indonesia, 28282
Actively Recruiting
10
Stella Maris Hospital
Makassar, South Sulawasi, Indonesia, 90111
Actively Recruiting
11
Bukit Asam Medika Hospital
Palembang, South Sumatra, Indonesia, 31716
Actively Recruiting
12
Advent Hospital
Bandung, West Java, Indonesia, 40131
Actively Recruiting
13
Borromeus Hospital
Bandung, West Java, Indonesia, 40131
Actively Recruiting
14
RSUD Syamsudin Hospital
Sukabumi, West Java, Indonesia, 43113
Actively Recruiting
15
Semen Padang Hospital
Padang, West Sumatra, Indonesia, 25161
Actively Recruiting
16
DrThong,Leow,Chiam & Partners
Kuala Lumpur, Kuala Lumpur, Malaysia, 50250
Actively Recruiting
17
Klinik Pembangunan Sdn. Bhd
Kuala Lumpur, Kuala Lumpur, Malaysia, 50490
Actively Recruiting
18
Pantai HKL
Kuala Lumpur, Kuala Lumpur, Malaysia, 59100
Actively Recruiting
19
Columbia Asia Hospital Seremban
Seremban, Negeri Sembilan, Malaysia, 70300
Actively Recruiting
20
Mawar Medical Centre
Seremban, Negeri Sembilan, Malaysia, 70300
Active, Not Recruiting
21
Bukit Tinggi Medical Centre
Klang, Selangor, Malaysia, 41200
Actively Recruiting
22
Mary Mediatrix Medical Center
Lipa, Batangas, Philippines, 4217
Actively Recruiting
23
Veterans Memorial Medical Center
Quezon City, Manila, Philippines, 1110
Actively Recruiting
24
Kangbuk Samsung Hospital
Seoul, Jongno District Seoul, South Korea, 03181
Actively Recruiting
25
Eunpyeong St. Mary's Hospital
Seoul, Seoul, South Korea, 03312
Actively Recruiting
26
Chonnam National University Hospital
Gwangju, South Korea, 61469
Actively Recruiting
27
Far Eastern Memorial Hospital (FEMH)
New Taipei City, Banqiao, Taiwan, 220
Actively Recruiting
28
Changhua Christian Hospital (CCH)
Changhua, Changhua County, Taiwan, 500
Actively Recruiting
29
Chang Gung Memorial Hospital-Chiayi branch (CGMH-CY)
Pozi, Chiayi County, Taiwan, 613
Not Yet Recruiting
30
Chung Gung Memorial Hospital-Linkou Branch (CGMH-LK)
Taoyuan, Guishan District, Taiwan, 333
Active, Not Recruiting
31
Hualien Tzu-Chi Hospital (HTCH)
Hualien City, Hualien County, Taiwan, 970
Actively Recruiting
32
Asia University Hospital (AUH)
Taipei, Nangang Dist., Taiwan, 115
Actively Recruiting
33
National Cheng Kung University Hospital (NCKUH)
Tainan, North District, Taiwan, 704
Actively Recruiting
34
Kaohsiung Medical University Hospital (KMUH)
Kaohsiung City, Sanmin District, Taiwan, 80756
Actively Recruiting
35
Taipei Medical University Hospital (TMUH)
Taipei, Xinyi District, Taiwan, 110
Actively Recruiting
36
Taichung Veterans General Hospital (TVGH)
Taichung, Xitun District, Taiwan, 407219
Actively Recruiting
37
Chi-Mei Medical Center (CMC)
Tainan, Yongkang Dist., Taiwan, 704
Active, Not Recruiting
38
MacKay Memorial Hospital (MMH)
Taipei, Zhongshan District, Taiwan, 104
Actively Recruiting
39
National Taiwan University Hospital (NTUH)
Taipei, Zhongzheng District, Taiwan, 100
Actively Recruiting
40
Vajira Hospital Namindradhiraj University
Dusit, Bangkok, Thailand, 10300
Actively Recruiting
41
Wetchakarunrasm Hospital
Nong Chok, Bangkok, Thailand, 10530
Actively Recruiting
42
Burapha University
Chon Buri, Changwat Chon Buri, Thailand, 20131
Actively Recruiting
43
Anand Mahidhol Hospital
Lopburi, Changwat Lop Buri, Thailand, 15000
Actively Recruiting
44
Central Chet Institute
Nonthaburi, Changwat Nonthaburi, Thailand, 11000
Actively Recruiting
45
Chiang Mai University
Chiang Mai, Chiang Mai, Thailand, 50200
Actively Recruiting
46
CanTho General Hospital
Can Tho, Can Tho City, Vietnam, 900000
Actively Recruiting
47
Hanoi Heart Hospital
Hanoi, Hanoi, Vietnam, 100000
Actively Recruiting
48
Cho Ray Hospital
Ho Chi Minh City, Ho Chi Minh, Vietnam, 700000
Completed
49
Hue Central Hospital
Huế, Hue, Vietnam, 530000
Actively Recruiting
Research Team
D
Dr Radhika Mehta
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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