Actively Recruiting
Led by Washington University School of Medicine · Updated on 2026-04-08
200
Participants Needed
2
Research Sites
52 weeks
Total Duration
W
Washington University School of Medicine
Lead Sponsor
U
University of Chicago
Collaborating Sponsor
This trial investigates adults with trigger finger, a condition where a finger locks due to swelling around the tendons. It compares two types of skin cuts used in surgery to release the finger pulley: a longitudinal incision along the finger and a transverse incision across the palm crease. The study aims to find which incision leads to better hand function, less pain, improved scar healing, and quicker return to normal activities. Participants will undergo surgery to release the pulley using one of the two incision types assigned randomly. Both surgeries follow the same techniques for the release and post-operative care. The trial will compare hand function about 6 weeks after surgery using the PROMIS Upper Extremity score. Secondary measures include pain levels, scar appearance, time to return to work, finger movement without pain, and complication rates. During the study, participants complete questionnaires about hand function and pain before and after surgery. Pain is recorded daily for the first three days and at follow-ups around 2, 6, and 12 weeks. Scars are assessed and photographed at these visits. Researchers will monitor complications and collect detailed data on recovery. The total follow-up lasts about 12 weeks after surgery to evaluate healing and satisfaction.
CONDITIONS
Prospective Randomized Trial Comparing Longitudinal vs. Transverse A1 Pulley Release
You may qualify if you...
You will not qualify if you...
Complete this quick 3-step screening to check your eligibility
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - Up to 1 week
Participants undergo standard open A1 pulley release surgery using either a longitudinal or transverse incision based on randomization, followed by standardized post-operative care.
Surgery visit plus daily pain assessments on days 1 to 3
Duration - Approximately 12 weeks
Participants are monitored for recovery including function, pain, scar healing, and complications through scheduled assessments.
In-person or virtual visits at approximately 2 weeks, 6 weeks, and 12 weeks
Total: 2 locations
1
The University of Chicago Medicine
Chicago, Illinois, United States, 60537
Actively Recruiting
2
Washington University and Barnes-Jewish Orthopedic Center
St Louis, Missouri, United States, 63110
Actively Recruiting
N
Nisha N Kale, MD
J
Jason Strezlow, MD
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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