Actively Recruiting
Prospective Real-World Study of HAIC With Raltitrexed or 5-Fluorouracil for the Treatment of Hepatocellular Carcinoma
Led by RenJi Hospital · Updated on 2024-08-07
1115
Participants Needed
2
Research Sites
156 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This study is a prospective cohort study aimed at comparing the efficacy and safety of RALOX-HAIC and FOLFOX-HAIC in the treatment of hepatocellular carcinoma. It is planned to enroll 1115 patients with BCLC Stage B or C hepatocellular carcinoma, who will receive FOLFOX-HAIC or RALOX-HAIC treatment.
CONDITIONS
Official Title
Prospective Real-World Study of HAIC With Raltitrexed or 5-Fluorouracil for the Treatment of Hepatocellular Carcinoma
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Adults aged 18 to 75 years
- Patients diagnosed with BCLC Stage B or C hepatocellular carcinoma
- Patients able to receive hepatic artery infusion chemotherapy with either RALOX or FOLFOX
- Patients without severe infections, serious cardiovascular or cerebrovascular diseases
- Patients without recent gastrointestinal bleeding or fistulas
- Patients with no history of active immunodeficiency or organ transplantation
- Patients without other active primary malignant tumors or with tumors treated curatively over 5 years ago
- Patients without severe physical or mental conditions that interfere with study participation
You will not qualify if you...
- Patients who request to stop study treatment
- Patients with disease progression deemed not benefiting from continuing treatment
- Patients experiencing adverse events or conditions making continued treatment unsuitable
- Pregnant female patients
- Patients with significant protocol deviations requiring treatment termination
- Patients who die or are lost to follow-up
- Patients in a study that is terminated
- Other conditions determined by the investigator requiring treatment termination
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 2 locations
1
Deparment of Liver Surgery, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University
Shanghai, China, 200127
Actively Recruiting
2
Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University
Shanghai, China, 200127
Actively Recruiting
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NON_RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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