Psoriatic arthritis.
Oliver FitzGerald, Alexis Ogdie, Vinod Chandran...
https://pubmed.ncbi.nlm.nih.gov/34385474Actively Recruiting
Age: 18Years +
All Genders
ID06730334
Prospective Study of Classification and Activity Assessment of Psoriatic Arthritis Based on Power Doppler Ultrasonography
Led by Nanjing Medical University · Updated on 2024-12-20
400
Participants Needed
2
Research Sites
247 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Psoriatic arthritis (PsA) is a complex inflammatory disease affecting about 30% of psoriasis patients. It involves various tissues and areas such as skin, nails, joints, spine, entheses, and fingers or toes. Researchers are conducting a prospective, observational, open-label study to examine disease activity, treatment response, and bone damage in PsA patients using Power Doppler ultrasonography (PDUS), a sensitive and non-invasive imaging technique. The study focuses on assessing PsA with PDUS to monitor disease features and treatment effects. There are no specific interventions or drugs assigned in this observational study. Instead, the study tracks disease characteristics and changes over time using imaging technology. Participants will undergo assessments including the Madrid Sonographic Enthesitis Index (MASEI) and DACTylitis glObal Sonographic (DACTOS) evaluations at 12 weeks. The study requires patients to attend visits, follow treatment plans, and complete laboratory tests and other procedures. Researchers will use these measures to understand disease activity and monitor bone destruction and treatment response in PsA.
CONDITIONS
Official Title
Prospective Study of Classification and Activity Assessment of Psoriatic Arthritis Based on Power Doppler (PD) Ultrasonography (PDUS)
Who Can Participate
Age: 18Years +
All Genders
Eligibility Criteria
You may qualify if you...
- Psoriatic arthritis patients as defined by CASPAR criteria
- Ability to follow the visit schedule, treatment plan, laboratory tests, and study procedures
- Provided informed consent to participate
You will not qualify if you...
- History of other arthritis within the last 12 months
- Presence of acute or chronic infectious diseases
- Pregnant or breastfeeding women
- Poor tolerance for venipuncture required for blood sampling during the study
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
1
2
3
Trial Site Locations
Total: 2 locations
1
Department of Rheumatology and Immunology, Jiangsu Province Hospital
Nanjing, Jiangsu, China, 210029
Actively Recruiting
2
Jiangsu Province Hospital
Nanjing, Jiangsu, China, 210029
Actively Recruiting
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Research Team
R
Rui Rui LIU, MD
Q
Qian ZHANG, MD
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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https://pubmed.ncbi.nlm.nih.gov/32862564Ultrasound dactylitis predicts bone erosion in early psoriatic arthritis: A longitudinal cohort study.
Qian Zhang, Cuilian Mao, Fengyun Lu...
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