Actively Recruiting

FEMALE
NCT06862089

A Prospective Study Evaluating the Impact of Conservative Management on Retained Products of Conception and EMV

Led by Fu Xing Hospital, Capital Medical University · Updated on 2025-06-15

120

Participants Needed

1

Research Sites

114 weeks

Total Duration

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AI-Summary

What this Trial Is About

The goal of this observational study is to learn about the therapeutic effects of the conservative treatment approach on pepole with retained products of conception (RPOC) and Enhanced myometrial vascularity (EMV). The main question it aims to answer is: Is it possible to achieve the natural resolution of RPOC by combining it with EMV through conservative treatment? Participants will receive conservative treatment (such as mifepristone, GnRH-a, or expectant management) following the initial diagnosis of RPOC and EMV, and the therapeutic efficacy of the conservative approach will be assessed after the completion of two menstrual cycles.

CONDITIONS

Official Title

A Prospective Study Evaluating the Impact of Conservative Management on Retained Products of Conception and EMV

Who Can Participate

FEMALE

Eligibility Criteria

Eligible

You may qualify if you...

  • Recent history of miscarriage or delivery within the past 8 weeks
  • Strong willingness to undergo conservative management
  • Hemodynamically stable
  • Signed informed consent form
Not Eligible

You will not qualify if you...

  • Heavy vaginal bleeding requiring immediate surgical intervention
  • Active pelvic or systemic infection such as fever over 38 0C or elevated CRP/WBC
  • Severe dysfunction of vital organs including heart, liver, or kidney
  • Known drug allergies or contraindications to proposed medications like misoprostol intolerance
  • Suspected ectopic pregnancy or gestational trophoblastic disease confirmed by ultrasound or b2-hCG levels
  • Placenta accreta spectrum disorders diagnosed during current pregnancy
  • History of uterine artery embolization

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Hysteroscopy Center, Fuxing Hospital, Capital Medical University

Beijing, China, 100086

Actively Recruiting

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Research Team

R

Rui Huang

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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