Actively Recruiting

Phase Not Applicable
Age: 18Years - 45Years
FEMALE
NCT06056635

A Prospective Study on the Role of Karl Storz Curved and Straight Fetoscopes (11508AAK and 11506AAK) for Fetoscopic Intrauterine Procedures

Led by Boston Children's Hospital · Updated on 2024-09-25

50

Participants Needed

1

Research Sites

141 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

In this research study, the investigators want to learn more about the role of new innovative surgical devices, the Karl Storz Curved and Straight Fetoscopes for in-utero surgery. A fetoscope is like a small telescope that can see inside of the uterus (womb) during minimally invasive surgery. The curved scope is used for patients with an anterior placenta (front of uterus), while the straight scope is used for patients with a posterior placenta (back of uterus). The scopes will be used to assist in procedures involving fetoscopic laser photocoagulation (FLP), which is a minimally invasive surgery that uses a small camera (fetoscope) to locate abnormal blood vessel connections in the placenta and seal them off using laser energy. These fetoscopes will be utilized in the diagnosis and management of various fetal conditions that can arise during pregnancy. Outcome data will be reported in a descriptive statistical analysis. The investigators will assess the surgical outcomes, short and long-term morbidity, complications, and gestational age of participants in order to evaluate the benefit of using these devices.

CONDITIONS

Official Title

A Prospective Study on the Role of Karl Storz Curved and Straight Fetoscopes (11508AAK and 11506AAK) for Fetoscopic Intrauterine Procedures

Who Can Participate

Age: 18Years - 45Years
FEMALE

Eligibility Criteria

Eligible

You may qualify if you...

  • Pregnant patient with a condition requiring in-utero surgery
  • Patient must be eligible for anesthesia
  • Patient and father of the fetus (if available) are able to provide signed informed consent
Not Eligible

You will not qualify if you...

  • Allergy or previous adverse reaction to any ancillary medication specified in this protocol that has no alternative
  • Preterm labor, preeclampsia, or uterine anomaly (e.g., large fibroid tumor) in the index pregnancy
  • Suspicion of major recognized congenital syndrome on ultrasound or MRI that is not compatible with postnatal life
  • Pre-pregnancy maternal BMI greater than 40
  • High risk for fetal hemophilia
  • Fetal aneuploidy or variants of known significance if an amniocentesis was performed
  • Contraindication to abdominal surgery or fetoscopic surgery

AI-Screening

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Trial Site Locations

Total: 1 location

1

Boston Children's Hospital

Boston, Massachusetts, United States, 02115

Actively Recruiting

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Research Team

B

Brittany Gudanowski

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

TREATMENT

Number of Arms

1

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