Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
NCT06214611

Prospective Validation of Adaptive Radiotherapy (ART) in Patients With Head and Neck Tumors

Led by University Hospital, Essen · Updated on 2024-09-27

50

Participants Needed

1

Research Sites

213 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Adaptive radiotherapy (ART) includes image-guided radiotherapy (IGRT) and also offers further possibilities for plan adaptation. A particularly high benefit can be expected for patients in whom the clinical target volume (CTV) can show a significant change in shape from fraction to fraction due to anatomical deviations. The shape and position constancy of the CTV during the course of the series is examined in this trial. Dosimetric disadvantages of this type have not been reported so far. The aim of this study is to identify patients who benefit from ART at an early stage and to select them for this method, and then to continue to offer ART to this patient group. If a relevant reduction in the minimum planning target volume (PTV) margins with ART compared to IGRT is demonstrated in this study, patients could be treated with ART.

CONDITIONS

Official Title

Prospective Validation of Adaptive Radiotherapy (ART) in Patients With Head and Neck Tumors

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • ECOG performance status 0-1
  • Histopathological confirmation of tumor
  • Willingness and ability to comply with study requirements
  • Presence of tumor in the head and neck region
  • Medical indication for radiotherapy
Not Eligible

You will not qualify if you...

  • Pregnancy

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Department for Radiotherapy, University Hospital Essen, National Center for Tumor Diseases (NCT) West

Essen, Germany / NRW, Germany, 45147

Actively Recruiting

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Research Team

M

Maja PD Dr. med. Guberina, PD Dr. med. (MD), specialist

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NON_RANDOMIZED

Model

CROSSOVER

Primary Purpose

TREATMENT

Number of Arms

2

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