Actively Recruiting
Prostate Cancer Screening for People at Genetic Risk for Aggressive Disease, PATROL Study
Led by University of Washington · Updated on 2025-11-10
450
Participants Needed
8
Research Sites
536 weeks
Total Duration
On this page
Sponsors
U
University of Washington
Lead Sponsor
N
National Cancer Institute (NCI)
Collaborating Sponsor
AI-Summary
What this Trial Is About
This study investigates ways to detect prostate cancer earlier in people at genetic risk for disease that forms, grows, or spreads quickly (aggressive). Studying samples of blood, urine, and/or tissue in the laboratory may help doctors further understand the genetics of prostate cancer and help identify ways to detect cancer earlier, thereby improving treatment and methods of early detection in the future.
CONDITIONS
Official Title
Prostate Cancer Screening for People at Genetic Risk for Aggressive Disease, PATROL Study
Who Can Participate
Eligibility Criteria
You may qualify if you...
- People with prostates aged 40 years or older
- Documented germline pathogenic variant in known or suspected genes linked to prostate cancer risk
You will not qualify if you...
- Prior diagnosis of prostate cancer
- Medical reasons preventing study procedures like prostate biopsy
- Cancer treatment with curative intent within past 12 months for any cancer except non-melanoma skin cancer
- Previous or current participation in a cancer prevention trial for genetic prostate cancer risk
- Unable to provide written informed consent
- Unable or unwilling to complete clinical care and study procedures as required
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 8 locations
1
City of Hope
Duarte, California, United States, 91010
Actively Recruiting
2
University of California, San Francisco
San Francisco, California, United States, 94143
Actively Recruiting
3
Northwestern
Chicago, Illinois, United States, 60611
Actively Recruiting
4
Massachusetts General Hospital
Boston, Massachusetts, United States, 02114
Actively Recruiting
5
OHSU Knight Cancer Institute
Portland, Oregon, United States, 97239
Actively Recruiting
6
University of Pennsylvania/Abramson Cancer Center
Philadelphia, Pennsylvania, United States, 19104
Actively Recruiting
7
University of Texas Health Science Center at San Antonio
San Antonio, Texas, United States, 78229
Terminated
8
Fred Hutch/University of Washington Cancer Consortium
Seattle, Washington, United States, 98109
Actively Recruiting
Research Team
S
Study Team Coordinator
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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