Actively Recruiting

Age: 18Years +
All Genders
ID07107685

Osteoarticular Sepsis in Intensive Care Units: A Retrospective Study of Deceased Patients

Led by Assistance Publique - Hôpitaux de Paris · Updated on 2026-06-01

150

Participants Needed

1

Research Sites

N/A

Total Duration

On this page

AI-Summary

What this Trial Is About

This observational, retrospective, multicenter study focuses on patients who have died after being admitted to critical care units with a diagnosis of prosthetic joint infection, including infections of hip, knee, or shoulder prostheses. The study aims to improve understanding of the profiles, care pathways, and outcomes of these patients by analyzing demographic, clinical, and biological data collected between 2018 and 2022. Results will be combined with data from a related study on living patients with osteoarticular sepsis to help identify at-risk populations and enhance management strategies. The study involves collecting and reviewing data from deceased patients who were hospitalized in intensive or continuing care units for at least 48 hours with prosthetic joint infection as a primary or associated diagnosis. There are no interventions or treatments administered, as this is an observational study. Data will be analyzed over a two-year period to describe epidemiological characteristics and clinical outcomes. Participants' data will be analyzed retrospectively, with no direct involvement in the study. Researchers will assess epidemiological information, bacterial strains identified during surgery, clinical outcomes, and mortality over two years. The study is sponsored by Assistance Publique - Hôpitaux de Paris and does not involve any follow-up or treatment for participants, as it focuses on deceased patients' medical records.

CONDITIONS

Brief Title

Prosthetic Joint Infection : Lessons From Deceased Patients in Critical Care.

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patient aged 18 years or older
  • Hospitalized in critical care (intensive or continuing care unit) between 2018 and 2022 for at least 48 hours
  • Prosthetic joint infection (hip, knee, or shoulder) as primary or associated diagnosis
  • Deceased patient who did not refuse data processing
Not Eligible

You will not qualify if you...

  • Infection involving osteosynthesis material
  • Infection involving spinal instrumentation
  • Patient with multiple infected prostheses
  • Recurrence of prosthetic infection with the same microorganism as a previous episode
  • Patient under legal protection
  • Pregnant or breastfeeding patient
  • Patient deprived of liberty

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person)

Surveillance

Duration - Up to 2 years

Participants who underwent intensive care with prosthetic joint infection are retrospectively observed through data collected from medical records.

No additional visits; data collected retrospectively

Trial Site Locations

Total: 1 location

1

Hôpital Lariboisière

Paris, France, France, 75010

Actively Recruiting

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Research Team

B

Benjamin SOYER, MD, Msc

B

Benjamin CHOUSTERMAN, MD, PhD

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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Frequently Asked Questions

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