Actively Recruiting

Phase Not Applicable
Age: 18Years - 90Years
All Genders
NCT04444349

Protective Effect of CoQ10 Against Negative Inflammatory Response and Organ Dysfunction in Cardiovascular Surgery (PANDA V)

Led by Nanjing Medical University · Updated on 2024-11-27

500

Participants Needed

4

Research Sites

256 weeks

Total Duration

On this page

Sponsors

N

Nanjing Medical University

Lead Sponsor

T

The First Affiliated Hospital with Nanjing Medical University

Collaborating Sponsor

AI-Summary

What this Trial Is About

Cardiovascular diseases are the leading causes of death and prescription drug use. Research on certain dietary supplements looks promising as a way to help reduce risk factors. Previous studies showed that CoQ10 levels were decreased in cardiovascular patients and worsening of mitochondrial dysfunction was observed. The overall objective of this study is to determine if supplementing with CoQ10 can reduce inflammatory risk factors in adults with cardiac surgery, independent of other dietary or physical activity changes.

CONDITIONS

Official Title

Protective Effect of CoQ10 Against Negative Inflammatory Response and Organ Dysfunction in Cardiovascular Surgery (PANDA V)

Who Can Participate

Age: 18Years - 90Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Adult men and women
  • Scheduled to receive cardiovascular surgery
  • Agree to participate in the surgery and sign the informed consent form
Not Eligible

You will not qualify if you...

  • Pregnant or planning on getting pregnant during the study
  • Having at least 2 traits of metabolic syndrome
  • Refused to participate in the surgery and refused informed consent

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 4 locations

1

Beijing Anzhen Hospital

Beijing, Beijing Municipality, China

Actively Recruiting

2

The First Affiliated Hospital of Guangzhou Medical University

Guangzhou, Guangdong, China

Actively Recruiting

3

The First Affiliated Hospital of Nanjing Medical University

Nanjing, Jiangsu, China, 210029

Actively Recruiting

4

West China Hospital of Sichuan University

Chengdu, Sichuan, China

Actively Recruiting

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Research Team

H

Hong Liu, MD

CONTACT

Y

Yong-feng Shao, MD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

TRIPLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

PREVENTION

Number of Arms

2

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