Actively Recruiting
Protein Needs Study
Led by University of Alberta · Updated on 2026-05-12
40
Participants Needed
1
Research Sites
492 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Severe muscle loss in patients with cancer has been associated with increased physical disability, extended hospitalization, infectious and noninfectious complications, increased risk of severe toxicity during cancer treatment, poor quality of life and shortened survival. Adequate protein is key to sustain muscle mass and overall health. However, current nutritional recommendations are not specific or evidence-based. The aim of this project is to determine the protein needs of patients with colorectal or breast cancer. Protein needs will be determined using a novel, non-invasive approach. Our results will inform nutritional recommendations and guidelines with the ultimate goal of improving outcomes for people with cancer.
CONDITIONS
Official Title
Protein Needs Study
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Outpatients aged 45 to 80 years
- Diagnosed with colorectal or breast cancer, stages II to III
- Attending the new patient clinic at the Cross Cancer Institute
- Able to complete baseline visits within about 4 weeks of starting chemotherapy or after at least 4 weeks post-surgery if not having chemotherapy
- Ambulatory and able to move independently
You will not qualify if you...
- Premenopausal women
- Received anti-cancer hormone treatment or immunotherapy within 4 weeks before the first baseline visit
- Renal impairment with creatinine clearance (eGFR) below 60 mL/min
- Abnormal glucose metabolism with fasting glucose over 6 mmol/L or HbA1c over 5.7%, or as reviewed by the study team
- Comorbidities or medications interfering with study participation or data quality (e.g., diabetes, severe obesity, hormone therapy, another active cancer)
- Unable or unwilling to provide urine, breath, and blood samples (e.g., oxygen tank, catheter)
- Unable to eat study meals (e.g., receiving parenteral or enteral nutrition, severe allergies)
- Substance dependence (e.g., alcohol, cigarettes, illicit drugs) affecting ability to follow study protocols
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
University of Alberta
Edmonton, Alberta, Canada, T6G 2R3
Actively Recruiting
Research Team
A
Anne Caretero, RD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
BASIC_SCIENCE
Number of Arms
1
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