Actively Recruiting

Phase Not Applicable
Age: 65Years +
MALE
Healthy Volunteers
NCT06431334

Protein Requirements Amongst Male Masters-Level Athletes Following a Cycling Exercise Bout as Determined by the Indicator Amino Acid Oxidation Technique

Led by McGill University · Updated on 2026-02-09

8

Participants Needed

1

Research Sites

101 weeks

Total Duration

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AI-Summary

What this Trial Is About

Masters level cyclists are a population above the age of 35 years who frequently participate in prolonged as well as heavy-volume training. Like most endurance-trained athletes, a greater recommended dietary allowance (RDA) for protein of 1.2-1.4 g/kg/bw is suggested. Dietary protein intake is vital for maximizing the benefits of training and ensuring optimal recovery. Dietary recommendations traditionally have been determined through nitrogen balance techniques, however, recent research indicates how this method is potentially underestimating protein requirements. Therefore, there is a need to reassess current dietary recommendations in order to meet the demands of physical activity for highly active populations. Recent efforts to understand protein requirements during rest and following exercise have been completed using the indicator amino acid technique (IAAO). This non-invasive method is reported to provide a robust measure of protein requirements. However, there is limited work in older (≥60 years) active populations. The purpose of this study is to measure the protein requirements in master cyclists, following an endurance training session, using the non-invasive IAAO technique.

CONDITIONS

Official Title

Protein Requirements Amongst Male Masters-Level Athletes Following a Cycling Exercise Bout as Determined by the Indicator Amino Acid Oxidation Technique

Who Can Participate

Age: 65Years +
MALE
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • BMI between 18.5 and 35 kg/m²
  • Healthy male masters-level cyclists aged 65 years or older
  • Training more than 4 days per week, cycling about 100 km per week
  • Stable body weight over the previous 6 months
  • Available for multiple metabolic trials (around 7 trials)
  • Able to travel to and from the laboratory facility
Not Eligible

You will not qualify if you...

  • Recent weight loss or gain greater than 5% of body weight
  • Uncontrolled high blood pressure
  • Two or more chronic diseases such as diabetes, osteoporosis, or dyslipidemia
  • Acute illnesses affecting protein metabolism like HIV, kidney problems, or influenza
  • Current use of anti-inflammatory medications
  • Unable to follow study protocol including alcohol, caffeine, or dietary restrictions
  • Regular tobacco use
  • Use of illicit drugs
  • Habitual protein intake of 3 grams per kilogram of body weight or more

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

McGill University

Montreal, Quebec, Canada, H3A 0G4

Actively Recruiting

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Research Team

T

Tyler A. Churchward-Venne, Ph.D.

CONTACT

D

Damian Papadopoulos, B.Sc

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

BASIC_SCIENCE

Number of Arms

1

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