Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
NCT07156552

Protein Supplementation and Resistance Training to Prevent Fat-Free Mass Loss Following Metabolic-Bariatric Surgery

Led by Radboud University Medical Center · Updated on 2025-09-05

400

Participants Needed

2

Research Sites

105 weeks

Total Duration

On this page

Sponsors

R

Radboud University Medical Center

Lead Sponsor

A

Amsterdam University Medical Centers (UMC), Location Academic Medical Center (AMC)

Collaborating Sponsor

AI-Summary

What this Trial Is About

The goal of this clinical trial is to investigate the effects of daily protein supplementation and participation in a weekly supervised resistance training program on the prevention of excessive muscle mass loss following bariatric surgery. Patients treated at one of the participating centers will be invited to participate and will be randomly assigned to one of two groups. Participants in group 1 will receive standard postoperative care as currently provided. Participants in group 2 will also receive standard care, but in addition, they will be asked to consume extra protein daily and take part in a supervised resistance training session once a week. Previous research has shown that approximately one in five patients undergoing bariatric surgery experiences excessive muscle loss after the surgery. It is known that resistance training and protein intake can help maintain and even improve muscle mass. However, limited research has been conducted on the combined effects of protein supplementation and resistance training in patients after bariatric surgery. Therefore, the aim of this trial is to determine whether participants receiving the additional intervention experience less muscle mass loss compared to those receiving standard care alone.

CONDITIONS

Official Title

Protein Supplementation and Resistance Training to Prevent Fat-Free Mass Loss Following Metabolic-Bariatric Surgery

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Scheduled for metabolic-bariatric surgery (Roux-en-Y gastric bypass or sleeve gastrectomy)
  • Participation in the NOK care program
  • Able to understand and perform study procedures
Not Eligible

You will not qualify if you...

  • Allergy or sensitivity to milk proteins or lactose intolerance
  • Diagnosed kidney (renal) insufficiency
  • Diagnosed intestinal diseases affecting protein absorption such as active inflammatory bowel disease

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 2 locations

1

Nederlandse Obesitas Kliniek

Amsterdam, Netherlands, 1043 DS

Not Yet Recruiting

2

Nederlandse Obesitas Kliniek

Nieuwegein, Netherlands, 3431

Actively Recruiting

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Research Team

J

J. H.M. Karregat, Dr.

CONTACT

B

B. M. de Roos, Drs.

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

PREVENTION

Number of Arms

2

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