Actively Recruiting
Protein Supplementation and Resistance Training to Prevent Fat-Free Mass Loss Following Metabolic-Bariatric Surgery
Led by Radboud University Medical Center · Updated on 2025-09-05
400
Participants Needed
2
Research Sites
105 weeks
Total Duration
On this page
Sponsors
R
Radboud University Medical Center
Lead Sponsor
A
Amsterdam University Medical Centers (UMC), Location Academic Medical Center (AMC)
Collaborating Sponsor
AI-Summary
What this Trial Is About
The goal of this clinical trial is to investigate the effects of daily protein supplementation and participation in a weekly supervised resistance training program on the prevention of excessive muscle mass loss following bariatric surgery. Patients treated at one of the participating centers will be invited to participate and will be randomly assigned to one of two groups. Participants in group 1 will receive standard postoperative care as currently provided. Participants in group 2 will also receive standard care, but in addition, they will be asked to consume extra protein daily and take part in a supervised resistance training session once a week. Previous research has shown that approximately one in five patients undergoing bariatric surgery experiences excessive muscle loss after the surgery. It is known that resistance training and protein intake can help maintain and even improve muscle mass. However, limited research has been conducted on the combined effects of protein supplementation and resistance training in patients after bariatric surgery. Therefore, the aim of this trial is to determine whether participants receiving the additional intervention experience less muscle mass loss compared to those receiving standard care alone.
CONDITIONS
Official Title
Protein Supplementation and Resistance Training to Prevent Fat-Free Mass Loss Following Metabolic-Bariatric Surgery
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Scheduled for metabolic-bariatric surgery (Roux-en-Y gastric bypass or sleeve gastrectomy)
- Participation in the NOK care program
- Able to understand and perform study procedures
You will not qualify if you...
- Allergy or sensitivity to milk proteins or lactose intolerance
- Diagnosed kidney (renal) insufficiency
- Diagnosed intestinal diseases affecting protein absorption such as active inflammatory bowel disease
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 2 locations
1
Nederlandse Obesitas Kliniek
Amsterdam, Netherlands, 1043 DS
Not Yet Recruiting
2
Nederlandse Obesitas Kliniek
Nieuwegein, Netherlands, 3431
Actively Recruiting
Research Team
J
J. H.M. Karregat, Dr.
CONTACT
B
B. M. de Roos, Drs.
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
PREVENTION
Number of Arms
2
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