Actively Recruiting
Proteomics Analysis of Human Tears in the Diagnosis and Management of Dry Eye Disease
Led by The Hong Kong Polytechnic University · Updated on 2025-09-16
75
Participants Needed
1
Research Sites
260 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
In this study, the initial tear proteome profiles in Dry Eye Disease (DED) patients, the safety and effectiveness of using an EC certificate DED treatment device in DED management, together with the associated global tear proteome changes, will be investigated.
CONDITIONS
Official Title
Proteomics Analysis of Human Tears in the Diagnosis and Management of Dry Eye Disease
Who Can Participate
Eligibility Criteria
You may qualify if you...
- OSDI score 13
- Failure of at least one diagnostic test: Non-invasive tear break-up time less than 10 seconds, or
- Tear osmolarity 308 mOsm/L or inter-ocular difference greater than 8 mOsm/L, or
- Conjunctival staining with lissamine green showing more than 9 spots, or corneal staining with fluorescein more than 5 spots, or lid wiper epitheliopathy with lissamine green 2 mm in length or 25% sagittal width
You will not qualify if you...
- Any active ocular infections, inflammations, or eyelid anomalies
- Pregnant or lactating women
- Uncontrolled or newly diagnosed systemic diseases or changes in long-term medications within the past 6 months
- Use of active implantable devices such as pacemakers or hearing aids
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
The Hong Kong Polytechnic University, Hong Kong,
Hong Kong, Hong Kong
Actively Recruiting
Research Team
S
Sung Hei Jimmy Tse
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
DIAGNOSTIC
Number of Arms
3
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