Actively Recruiting

Phase Not Applicable
All Genders
NCT04852406

Protocol-based Management and Perioperative Outcomes in Patients With Chronic Antithrombotic Therapy

Led by Peking University First Hospital · Updated on 2025-07-31

526

Participants Needed

1

Research Sites

245 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The purpose of this pragmatic interventional study is to evaluate whether a protocol-based management of antithrombotic drugs can reduce a composite of perioperative outcomes in patients with chronic antithrombotic therapy before surgery.

CONDITIONS

Official Title

Protocol-based Management and Perioperative Outcomes in Patients With Chronic Antithrombotic Therapy

Who Can Participate

All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients with ongoing antithrombotic therapy for cardiovascular or cerebrovascular diseases for more than 2 weeks
  • Patients with one or more of the following: non-valvular atrial fibrillation with CHA2DS2-VASc score >4; post-artificial valve replacement; recent venous thromboembolism or high-risk factors needing long-term anticoagulation; coronary heart disease with recent stent, thrombolytic therapy, coronary artery bypass, or heart attack; recent stroke or revascularization; peripheral arterial disease
  • Patients scheduled for intra-abdominal surgery including general and urologic surgery
  • Patients who provide written informed consent
Not Eligible

You will not qualify if you...

  • Patients who refuse to participate
  • Patients requiring emergency surgery
  • Patients unable to complete preoperative assessment and follow-up
  • Patients deemed unsuitable for participation by investigators or attending doctors

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Peking University First Hospital

Beijing, Beijing Municipality, China, 100034

Actively Recruiting

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Research Team

H

Hong Zhang, MD

CONTACT

H

Huai-Jin Li, MD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

NON_RANDOMIZED

Model

PARALLEL

Primary Purpose

PREVENTION

Number of Arms

2

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Protocol-based Management and Perioperative Outcomes in Patients With Chronic Antithrombotic Therapy | DecenTrialz