International Observational Study on HIV and Other Infections in People Vulnerable to HIV Tracking New HIV Infections and Related Health Outcomes in Ages 14 to 55

What this Trial Is About

Researchers are conducting an observational study called the Multinational Observational Cohort of HIV and Other Infections MOCHI to understand the number of new HIV infections among people vulnerable to acquiring HIV. This study is carried out across multiple international sites and focuses on individuals aged 14 to 55 years who engage in behaviors that increase their risk of HIV. It aims to gather information on HIV incidence as well as other sexually transmitted infections STIs. The study is divided into two steps. Step 1 enrolls participants aged 14 to 55 years who are vulnerable to HIV and evaluates them every 12 weeks for HIV and other STIs. Participants diagnosed with HIV in Step 1 move to Step 2, where they receive more frequent evaluations including viral load and other HIV-related tests every four weeks for 12 weeks, then every 12 weeks, with a total follow-up of 48 weeks in Step 2. Participants will attend regular visits for testing and evaluation throughout the study period. In Step 1, evaluations occur every 12 weeks, while in Step 2, participants have more frequent visits for detailed monitoring of their HIV status and viral load. Researchers will measure HIV incidence, STI prevalence, and willingness to participate over a 10-year period. The study includes collecting information on risk behaviors and monitoring participants health through laboratory tests and questionnaires.

Protocol RV 583 Multinational Observational Cohort of HIV and Other Infections