Proton and Photon Consortium Registry for Children and Young Adults Treated With Radiation Therapy

What this Trial Is About

This research aims to gather detailed information about children treated with radiation therapy for cancer to better understand and compare different radiation types, including Proton Beam Radiation Therapy PBRT. PBRT has shown promise in previous studies for targeting radiation more precisely and possibly causing fewer long-term side effects, but more data is needed to confirm these findings. The study collects data from multiple centers to describe the population receiving radiation and support collaborative research efforts. Participants will receive cancer treatment and follow-up care as determined by their doctors according to standard practices at their clinics. The study records all treatments, including surgeries and chemotherapy before or after radiation therapy. Data collection includes patient demographics, diagnosis, imaging, lab tests, treatment details, side effects, and additional therapies received alongside radiation. Participants will be followed over time with annual chart reviews by study staff to update health status, treatment outcomes, side effects, and development of new medical conditions or cancers. The study aims to track long-term outcomes and quality of life for children treated with radiation. Data access is shared among participating centers and authorized entities to support the research. The study plans to establish and maintain this registry for many years, collecting data throughout participants lives.

Proton and Photon Consortium Registry (PPCR): A Multi Center Registry of Pediatric Patients Treated With Radiation Therapy