Actively Recruiting

Phase 2
Age: 18Years +
FEMALE
NCT05758688

PROton Therapy for Post Surgical Treatment of GYNecologic Cancer

Led by Abramson Cancer Center at Penn Medicine · Updated on 2026-03-12

25

Participants Needed

3

Research Sites

155 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This is a single institution, multi-center, Phase II, single-arm study, using Whole Pelvis (WP) Pencil Beam Scanning Proton Radiation (PBS PRT) in the post-surgical, adjuvant setting for definitive treatment of gynecologic cancers. The purpose of this study is to estimate rate of acute clinician-reported gastrointestinal (GI) toxicity using WP PBS PRT in the definitive treatment of gynecologic cancers in the post-surgical, adjuvant setting.

CONDITIONS

Official Title

PROton Therapy for Post Surgical Treatment of GYNecologic Cancer

Who Can Participate

Age: 18Years +
FEMALE

Eligibility Criteria

Eligible

You may qualify if you...

  • Histologically confirmed cervical or endometrial cancer
  • Indication for adjuvant whole pelvic radiation therapy, with or without systemic therapy
  • Age of 18 years or older
  • Written informed consent
  • ECOG of 0-2 within 3 months of enrolling
Not Eligible

You will not qualify if you...

  • Prior course of pelvic radiation
  • Metastatic disease outside of the pelvis
  • Active inflammatory bowel disease
  • Incapacity to provide informed consent

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

1
2
3
+1

Trial Site Locations

Total: 3 locations

1

Virtua Health

Voorhees Township, New Jersey, United States, 08043

Actively Recruiting

2

Lancaster General Health - Ann B. Barshinger Cancer Institute

Lancaster, Pennsylvania, United States, 17601

Actively Recruiting

3

University of Pennsylvania

Philadelphia, Pennsylvania, United States, 19104

Actively Recruiting

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Research Team

P

Project Manager

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

TREATMENT

Number of Arms

1

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