Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
NCT07412314

Proton Therapy for Recurrent Nasopharyngeal Carcinoma

Led by Guangzhou Concord Cancer Center · Updated on 2026-03-09

52

Participants Needed

2

Research Sites

156 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The above studies show that most of the supportive evidence for the reduction of toxicity and improvement of efficacy of proton therapy for recurrent Nasopharyngeal carcinoma(NPC) comes from various observational and retrospective studies, lacking high-level evidence-based medical evidence. The conduct of this study will explore the safety and efficacy of intensity-modulated proton radiotherapy for recurrent NPC and provide more high-quality evidence-based medical evidence for proton therapy of recurrent cancer.

CONDITIONS

Official Title

Proton Therapy for Recurrent Nasopharyngeal Carcinoma

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Non-metastatic squamous cell carcinoma of the nasopharynx confirmed by biopsy, stage 63; T2b and/or positive lymph nodes
  • Pathological type WHO I-III
  • Eastern Cooperative Oncology Group (ECOG) performance status score 0-1
  • Age 18 years or older
  • Expected survival of at least 6 months
  • Tumor range and size evaluated before treatment
  • Nutritional and physical condition able to tolerate recommended radiotherapy and chemotherapy
Not Eligible

You will not qualify if you...

  • Evidence of distant metastasis at stage IVc
  • Recurrence isolated to cervical lymph nodes
  • Participation in other interventional tumor trials
  • History of other malignant tumors within past 5 years (excluding melanoma skin cancer) or untreated active infections
  • Tumors originating from the head and neck region not treated

AI-Screening

AI-Powered Screening

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Trial Site Locations

Total: 2 locations

1

Guangzhou Concord Cancer Center

Guangzhou, Guangdong, China

Actively Recruiting

2

Guangzhou concord cancer center

Guanzhou, Guangzhou, China

Actively Recruiting

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Research Team

T

Taize Yuan, M.D., Ph.D.

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

TREATMENT

Number of Arms

1

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