Actively Recruiting
Provocative Tests for HFpEF
Led by Istituto Auxologico Italiano · Updated on 2025-08-03
500
Participants Needed
1
Research Sites
259 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Diagnosing heart failure with preserved ejection fraction (HFpEF) in patients complaining exertional breathlessness can be challenging: diagnostic algorithms and scores have low sensitivity, and ageing-associated comorbidities can complicate the interpretation of symptoms. Thus, exercise right heart catheterization (RHC) or invasive cardiopulmonary exercise test (iCPET) have been advocated as gold-standard methods for HFpEF diagnosis. However, exercise RHC and iCPET are still not widely standardized methods, with results mainly coming from US cohorts (that may differ from Italian cohorts), and other provocative tests (e.g. non-invasive CPET, passive leg raising) may offer complementary diagnostic information.
CONDITIONS
Official Title
Provocative Tests for HFpEF
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Experiencing breathlessness (dyspnea)
You will not qualify if you...
- Known diagnosis of heart failure with preserved ejection fraction (HFpEF)
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Ospedale San Luca IRCCS Istituto Auxologico Italiano
Milan, Italy, 20149
Actively Recruiting
Research Team
S
Sergio Caravita, MD, PhD
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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