Actively Recruiting

Phase Not Applicable
Age: 20Years - 75Years
All Genders
Healthy Volunteers
NCT04446273

Proximal Priority Versus Distal Priority Robotic Priming Effects in Patients With Chronic Stroke

Led by National Taiwan University Hospital · Updated on 2026-02-25

72

Participants Needed

4

Research Sites

312 weeks

Total Duration

On this page

Sponsors

N

National Taiwan University Hospital

Lead Sponsor

N

National Health Research Institutes, Taiwan

Collaborating Sponsor

AI-Summary

What this Trial Is About

This is a single-blind randomized comparative efficacy study involving 54-72 participants with chronic stroke. Participants will be randomized into proximal priority robotic group or distal priority robotic group and receive 18 intervention sessions (90 min/d, 3 d/wk for 6 weeks). The Fugl-Meyer Assessment Upper Extremity subscale, Medical Research Council Scale, Revised Nottingham Sensory Assessment, and Wolf Motor Function Test will be administered at baseline, after treatment, and at the 3-month follow-up. Two-way repeated-measures analysis of variance and the Chi-Square Automatic Interaction Detector Method will be used to examine the comparative efficacy and predictors of outcome, respectively, after intervention.

CONDITIONS

Official Title

Proximal Priority Versus Distal Priority Robotic Priming Effects in Patients With Chronic Stroke

Who Can Participate

Age: 20Years - 75Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Age between 20 and 75 years old
  • More than 3 months after first unilateral ischemic or hemorrhagic stroke
  • Moderate to severe upper extremity motor impairment (Fugl-Meyer Assessment score between 18 and 56)
  • No severe spasticity (modified Ashworth Scale score less than 3) in affected shoulder, elbow, wrist, or fingers
  • Able to follow instructions (Mini-Mental State Examination score greater than 24)
  • No upper extremity fractures in the past 3 months
  • Not currently participating in other medication or rehabilitation studies
Not Eligible

You will not qualify if you...

  • Presence of other neurological, neuromuscular, or orthopedic diseases such as epilepsy
  • Severe health or physical conditions that could prevent participation in the study

AI-Screening

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Trial Site Locations

Total: 4 locations

1

National Taiwan University Hospital

Taipei, Taipei, Taiwan, 100

Actively Recruiting

2

Taipei Tzu Chi Hospital

New Taipei City, Taiwan

Actively Recruiting

3

Fongyuan Hospital

Taichung, Taiwan

Actively Recruiting

4

Taipei Municipal Wan Fang Hospital

Taipei, Taiwan, 116

Actively Recruiting

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Research Team

K

Kehchung Lin, ScD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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