Actively Recruiting
PRP for Glenohumeral Osteoarthritis
Led by Hospital for Special Surgery, New York · Updated on 2025-10-06
135
Participants Needed
1
Research Sites
174 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The glenohumeral joint is the third most common large joint to be affected by OA. Conservative treatments include physical activity, corticosteroid injections, and medications. PRP is an emerging treatment that has shown efficacy in different musculoskeletal conditions. The use of PRP for glenohumeral OA has been described sparingly in the literature but has shown efficacy in a couple studies and case reports. However, all of the previous studies investigating PRP for glenohumeral OA have focused on low-dose PRP preparations (\~3X), and none have compared PRP treatment to saline treatment. This study aims to compare outcomes following single injections of low-dose PRP, high-dose PRP, or saline in patients with glenohumeral osteoarthritis.
CONDITIONS
Official Title
PRP for Glenohumeral Osteoarthritis
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age between 18 and 100 years
- Average pain score of 5 or higher out of 10 due to glenohumeral osteoarthritis or cartilage damage
- Shoulder pain lasting at least 3 months after symptom onset that has not improved with conservative treatments, including physical therapy
- MRI of the affected shoulder joint
- Temporary relief of symptoms after a diagnostic intra-articular injection into the shoulder joint
- Access to email or internet network
You will not qualify if you...
- Unable to avoid non-steroidal anti-inflammatory drugs for 2 weeks before and 1 month after the injection
- Previous platelet-rich plasma injection in the affected joint
- Steroid injection in the affected joint within 3 months before the injection
- Hyaluronic acid injection in the affected joint within 6 months before the injection
- Involved in workers' compensation or active legal cases related to the affected shoulder
- History of using Plavix medication
- Known uncontrolled systemic illnesses such as uncontrolled diabetes, HIV, vasculitis, or autoimmune/autoinflammatory diseases
- Presence of recent fractures or major mechanical deformities in the shoulder
- Uncontrolled cervical spine disorders
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Hospital for Special Surgery
New York, New York, United States, 10021
Actively Recruiting
Research Team
J
Jonathan Kirschner, MD
CONTACT
J
Jennifer Cheng
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
TRIPLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
3
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