Actively Recruiting

Phase Not Applicable
Age: 11Years - 14Years
All Genders
NCT05987761

PRT for Adolescents With High Functioning Autism

Led by Stanford University · Updated on 2024-03-28

76

Participants Needed

1

Research Sites

156 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The purpose of this study is to identify improvement in behavioral and social function and changes in the brain following Pivotal Response Treatment (PRT) for Adolescents in highly verbal adolescents with autism spectrum disorder (ASD).

CONDITIONS

Official Title

PRT for Adolescents With High Functioning Autism

Who Can Participate

Age: 11Years - 14Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Clinical diagnosis of autism spectrum disorder with higher functioning/low support needs
  • Full Scale IQ greater than 80 on the Wechsler Abbreviated Scale of Intelligence (WASI-II)
  • Right-handed
  • No metal or unremovable metal in the body (e.g., braces)
  • First language is English
  • Must live in the San Francisco Bay Area
  • Able and willing to attend weekly intervention sessions for 9 weeks
  • Adolescent interested in improving social skills
  • No major contraindications for MRI
  • Diagnosis of ASD confirmed by ADOS-2 and ADI-R
  • No evidence of genetic, metabolic, or infectious cause for autism
  • Primary diagnosis of ASD
  • No significant difficulties during pregnancy, labor, delivery, or immediate neonatal period
  • Stable treatment (e.g., ABA, speech therapy, medications) for at least 1 month before baseline with no planned changes
  • Score of 50% or below on at least 4 of 9 social target areas in structured laboratory observations at pre-measures
Not Eligible

You will not qualify if you...

  • History of claustrophobia, previous head injury, serious neurological or medical illness
  • Birth weight less than 4 pounds and/or gestational age less than 34 weeks
  • Left-handed
  • Presence of braces or any metal in the body

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Stanford Research Park

Palo Alto, California, United States, 94304

Actively Recruiting

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How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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