Actively Recruiting
prTMS as an Intervention for Bradykinesia in Parkinson's Disease
Led by Danish Research Centre for Magnetic Resonance · Updated on 2026-02-09
27
Participants Needed
1
Research Sites
71 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This study investigates the use of patterned repetitive transcranial magnetic stimulation (prTMS) as an intervention for bradykinesia in Parkinson's Disease (PD). More specifically, the study aims to determine whether prTMS over the supplementary motor area (SMA) can reduce severity of bradykinesia in PD patients. This approach may open for more targeted and effective treatment of bradykinesia in PD.
CONDITIONS
Official Title
prTMS as an Intervention for Bradykinesia in Parkinson's Disease
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Above 18 years of age
- Clinically established or probable Parkinson's Disease according to the Movement Disorder Society
- Stable antiparkinsonian medicine for at least four weeks
- Signed informed consent
You will not qualify if you...
- Psychiatric disorders
- Current use of antipsychotic medication, Donepezil, or GABAergic agents (e.g., pregabalin, gabapentin)
- Frequent benzodiazepine or opioid use more than once per week regularly
- History of neurological disease other than Parkinson's Disease
- Past or present mental illness
- History of epilepsy or conditions increasing seizure risk with TMS
- Close relatives with epilepsy or increased seizure risk
- Contraindications for MRI or TMS
- Female participants of childbearing age who are pregnant or not using contraception
- Refusal to be informed about new health-related information or accidental findings during the study
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
DRCMR
Hvidovre, Denmark, 2650
Actively Recruiting
Research Team
A
Ann-Charlot Rughaven, M.Sc.
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
CROSSOVER
Primary Purpose
TREATMENT
Number of Arms
3
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here