Actively Recruiting
"Pseudo-scanner" MRI Sequences for the Detection of Bone Lesions in Multiple Myeloma
Led by Cliniques universitaires Saint-Luc- Université Catholique de Louvain · Updated on 2026-04-24
45
Participants Needed
1
Research Sites
131 weeks
Total Duration
On this page
Sponsors
C
Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Lead Sponsor
G
General Electric
Collaborating Sponsor
AI-Summary
What this Trial Is About
Recent work has confirmed the diagnostic performance of pseudo-CT sequences for detecting osteolytic lesions. Their integration into whole body MRI (WB MRI) could transform the diagnostic approach to MM, by allowing a combined assessment of bone marrow involvement, tissue viability and osteolysis, during a single non-irradiating imaging examination. Since the preliminary work mentioned above, optimizations have been made to the pseudo-CT sequences, including the addition of deep learning (correcting noise in the images) and the correction of chemical shift artifact (linked to the coexistence of hydrated tissue and fatty tissue), which carry real hope of improving their diagnostic potential and accuracy.
CONDITIONS
Official Title
"Pseudo-scanner" MRI Sequences for the Detection of Bone Lesions in Multiple Myeloma
Who Can Participate
Eligibility Criteria
You may qualify if you...
Patient with newly diagnosed multiple myeloma, for whom bone imaging is required for staging.
- Recurrent patient after intensive treatment (high dose chemotherapy, bone marrow transplant, etc.).
- Patient requiring a PET / CT considered as the technique of choice in these stages of the disease.
You will not qualify if you...
- Implanted material incompatible with MRI.
- Severe claustrophobia.
- Pregnant women
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Cliniques universitaires Saint-Luc
Brussels, Belgium
Actively Recruiting
Research Team
F
Frédéric Lecouvet
CONTACT
P
Perrine Triqueneaux
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
DIAGNOSTIC
Number of Arms
1
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