Actively Recruiting
Psilocybin-Assisted Therapy for Physician Well-Being and Burnout
Led by University of California, San Diego · Updated on 2026-01-20
10
Participants Needed
1
Research Sites
76 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Through an open-label study involving a small group of UCSD physicians experiencing burnout, the investigators will evaluate the feasibility, safety, and preliminary effectiveness of PAT to reduce burnout symptoms.
CONDITIONS
Official Title
Psilocybin-Assisted Therapy for Physician Well-Being and Burnout
Who Can Participate
Eligibility Criteria
You may qualify if you...
- UCSD faculty physician aged 21 to 70 years
- Meets criteria for physician burnout
- Experiencing burnout symptoms for more than 6 months
- Able to complete all required study visits
- No prior diagnosis of serious mental illness or substance use disorder
- Not currently taking psychotropic or serotonin syndrome-associated medications such as SSRIs, SNRIs, dextromethorphan, linezolid, tramadol, or meperidine
You will not qualify if you...
- Previous inpatient psychiatric hospitalization
- Diagnosis of psychotic disorder, bipolar spectrum disorder, severe personality disorder, or other severe psychiatric disorders
- Elevated suicide risk
- First-degree family history of psychosis or bipolar disorder
- Use of psilocybin or other psychedelics in the past 10 years
- Currently pregnant, nursing, planning pregnancy, or having unprotected sexual intercourse in the last 3 months
- Planning to donate sperm within 3 months following the study
- Known cardiovascular disease or clinically significant arrhythmia
- History of seizure disorder
- Use of recreational illicit drugs
- Abnormal vital signs, ECG, physical exam, or lab test results during screening
- Any other clinically significant illnesses that pose risk to the participant
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
UC San Diego
San Diego, California, United States, 92037
Actively Recruiting
Research Team
J
Jessie Kim
CONTACT
C
Cory Weissman
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
TREATMENT
Number of Arms
1
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