Actively Recruiting
Psychopharmacotherapy for Depressive Patients
Led by Chonnam National University Hospital · Updated on 2024-04-18
400
Participants Needed
1
Research Sites
438 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The primary purpose of this study is to compare the short (12 week) and long-term (1-year) efficacy and the tolerability between stepwise psychopharmacotherapy and antidepressant monotherapy for 12 weeks in adult patients with major depressive disorders, stratified by the multimodal serum biomarker scores.
CONDITIONS
Official Title
Psychopharmacotherapy for Depressive Patients
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age 19 to 65 years
- Diagnosis of major depressive disorder by study psychiatrists according to DSM-IV
- Score of 17 or higher on the Hamilton Depression Rating Scale-17
- Ability to understand the study purpose and provide informed consent
- Starting antidepressant treatment for current episode or no psychotropic use except sleep pills or benzodiazepines within 1 month before participation
You will not qualify if you...
- Diagnosis of bipolar disorder, schizophrenia, schizoaffective disorder, schizophreniform disorder, psychotic disorder not otherwise specified, or other psychotic disorders
- Current major depressive disorder with psychotic features
- History of organic psychosis, epilepsy, or seizure disorder
- Current anorexia nervosa or obsessive compulsive disorder
- Unstable or uncontrolled medical condition
- Severe physical illness preventing psychiatric assessment or medication compliance
- History of anticonvulsant treatment
- Electroconvulsive therapy for current depressive episode
- Hospitalization for psychiatric diagnoses other than depressive disorder
- High risk of suicide, self-harm, or homicide as assessed by investigator
- Pregnant or breastfeeding
- Lack of treatment information for current depressive episode
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Chonnam National University Hospital
Gwangju, South Korea, 61469
Actively Recruiting
Research Team
J
Jae-Min Kim, MD, PhD
CONTACT
H
Hee-Ju Kang, MD, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
TRIPLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
4
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