Actively Recruiting
PT150 Drug for Use in Alcohol Use Disorder
Led by Pop Test Oncology LLC · Updated on 2025-05-22
34
Participants Needed
1
Research Sites
182 weeks
Total Duration
On this page
Sponsors
P
Pop Test Oncology LLC
Lead Sponsor
U
University of Kentucky
Collaborating Sponsor
AI-Summary
What this Trial Is About
The goal of this study is to learn if PT150 can reduce the behavioral and physical effects of stress, alcohol, and alcohol use in people with alcohol use disorder.
CONDITIONS
Official Title
PT150 Drug for Use in Alcohol Use Disorder
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Meet diagnostic criteria for moderate or severe alcohol use disorder (AUD) per DSM-5
- Not seeking treatment for AUD at the time of the study
- English-speaking
- Between 21 and 55 years old
- Abstinent from alcohol no more than 3 days per week on average
- Physically and psychiatrically healthy except for AUD or tobacco use disorder
- ECG within normal limits as read by a cardiologist
- Body mass index between 19 and 35
- Using an effective form of birth control if female
- Able to abstain from alcohol for 12 hours before sessions
- No contraindications to alcohol or PT150
You will not qualify if you...
- Meet criteria for substance use disorders (except nicotine or AUD) requiring medical intervention or risking participant well-being
- Abnormal blood chemistry, complete blood count, or urinalysis deemed clinically significant
- History or current serious physical disease (e.g., cardiovascular issues, seizures, head trauma, CNS tumors)
- Current or past psychiatric disorder interfering with participation (e.g., schizophrenia, bipolar disorder, major depression)
- Suicidal thoughts in the past 90 days
- Pregnant or nursing
- Unwilling or unable to comply with study procedures
- Score above 6 on the Clinical Institute Withdrawal Assessment for Alcohol Revised (CIWA-Ar) before experimental sessions
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
University of Kentucky
Lexington, Kentucky, United States, 40506
Actively Recruiting
Research Team
M
Mark Fillmore, PhD
CONTACT
K
Kelsey Padgett, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
TRIPLE
Allocation
RANDOMIZED
Model
CROSSOVER
Primary Purpose
TREATMENT
Number of Arms
2
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