Comparing Prostatic Urethral Lift and TURP for Treating Urinary Retention in Men with Benign Prostatic Hyperplasia

What this Trial Is About

Researchers are conducting a prospective, randomized controlled trial to compare two treatments for benign prostatic hyperplasia BPH in male patients with urinary retention. The study aims to evaluate the catheter-free rates after treatment with prostatic urethral lift PUL versus transurethral resection of the prostate TURP. Secondary goals include comparing complications, cost effectiveness, patient satisfaction, symptom scores, quality of life, and bladder function over time. Participants will be randomly assigned to one of two groups the prostatic urethral lift group, where permanent implants made of special materials will be placed under local anesthesia or monitored anesthetic care or the TURP group, where tissue is removed using surgical resection under spinal or general anesthesia. The number of implants during PUL varies based on findings during the procedure. Follow-up visits are scheduled at multiple time points up to 5 years after surgery. During the study, participants will undergo assessments including questionnaires, uroflowmetry tests, and occasional urodynamic studies. These evaluations will occur before treatment and at 1 month, 3 months, 6 months, 1 year, 2 years, 3 years, 4 years, and 5 years post-treatment. Researchers will monitor catheter-free rates, complications, patient-reported symptoms and satisfaction, quality of life, and bladder function to understand the long-term effects of both treatments.

PUL vs TURP in BPH Patients With Urinary Retention