Actively Recruiting
Pulmonary Rehabilitation in Advanced Non-small Cell Lung Cancer Patients
Led by Instituto Nacional de Cancerologia de Mexico · Updated on 2026-04-08
94
Participants Needed
1
Research Sites
592 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Lung cancer (LC) is usually diagnosed in advanced stages and continues to be the leading cause of cancer related deaths worldwide. Cancer cachexia are frequent among patients with LC affecting up to 80% of patients with advanced stage disease, and it has been related with higher risk of complications, length of hospital stay, and worst overall survival. During cancer cachexia, both muscle and fat mass can be wasted, however, the loss of muscle mass has been associated to higher treatment related toxicity, loss of functional status, shorter progression free survival and overall survival in different types of cancer under various treatments. Hence, preservation of muscle mass and function should be an important focus of the multidisciplinary treatment of patients with LC. Pulmonary rehabilitation (PR) has been known to improve pulmonary function, reduce fatigue and improve exercise tolerance in patients with LC undergoing curative surgery. However, few studies have focused on the efficacy of PR on patients with advanced cancer undergoing palliative care with chemotherapy or targeted therapies.
CONDITIONS
Official Title
Pulmonary Rehabilitation in Advanced Non-small Cell Lung Cancer Patients
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Confirmed diagnosis of advanced non-small-cell lung cancer
- Good performance status (ECOG 0-1)
- Life expectancy greater than 12 weeks
- Eligible to receive chemotherapy or tyrosine kinase inhibitors
- Recent ECG showing no arrhythmia
You will not qualify if you...
- Symptomatic brain metastasis
- Uncontrolled pain with Visual Analog Scale greater than 5
- Uncontrolled hypertension greater than 140/100 mmHg
- Regular moderate to intense physical activity at least 3 days per week
- Not living in Mexico City or unable to attend therapy sessions
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Instituto Nacional de Cancerología
Mexico City, Mexico City, Mexico, 14080
Actively Recruiting
Research Team
O
Oscar Arrieta
CONTACT
D
Diana Flores
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
SUPPORTIVE_CARE
Number of Arms
2
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