Actively Recruiting

Phase Not Applicable
Age: 18Years - 90Years
All Genders
NCT04615130

PUlmonary REhabilitation in Patients Suffering From Post-PE Syndrome

Led by Medical University of Vienna · Updated on 2025-09-26

48

Participants Needed

1

Research Sites

343 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This study is a multicenter, parallel, randomized waitlist-controlled trial that primarily focuses on the short-term benefit of outpatient pulmonary rehabilitation (PR) on patients after acute pulmonary embolism. Patients will be randomized into an intervention and a control group. The intervention group will receive 6 weeks of outpatient PR, while patients in the other treatment arm will serve as a control. After completion of the randomized study, the second arm will undergo PR as well.

CONDITIONS

Official Title

PUlmonary REhabilitation in Patients Suffering From Post-PE Syndrome

Who Can Participate

Age: 18Years - 90Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Diagnosed with post-PE syndrome (excluding those previously diagnosed with CTEPH) by post-PE functional impairment, cardiac impairment, or chronic thromboembolic disease criteria
  • Able to start rehabilitation between 12 and 36 weeks after initial pulmonary embolism event
Not Eligible

You will not qualify if you...

  • Diagnosed with CTEPH
  • Chronic pulmonary diseases such as COPD, interstitial lung diseases, or severe asthma (FEV1 ≤ 80%)
  • Active cancer
  • Pregnancy
  • Myocardial infarction or cardiac surgery within one year prior to inclusion
  • Congenital heart disease or congestive heart failure
  • History of stroke
  • Previous inpatient or outpatient pulmonary rehabilitation
  • Acute or decompensated disease states with severe functional restrictions of organs (e.g., heart, kidney, liver insufficiency), unstable angina, unstable arrhythmias, acute spinal cord injury, untreated hormonal or psychological disorders
  • Open tuberculosis
  • Active infectious diseases or acute inflammatory processes
  • Stressful or time-consuming therapies that impair rehabilitation ability (e.g., chemotherapy or radiation after malignancy)
  • Physical or mental impairments preventing active rehabilitation participation
  • Lack of motivation for therapy
  • Massive incontinence
  • Drug or alcohol addiction

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Therme Wien Med

Vienna, Austria

Actively Recruiting

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Research Team

S

Stephan Nopp, Dr.

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

DOUBLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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PUlmonary REhabilitation in Patients Suffering From Post-PE Syndrome | DecenTrialz