Actively Recruiting

Age: 18Years +
All Genders
ID06761144

Pulmonary Thromboembolism in Cancer Patients: Early Rule-out From the Emergency Department

Led by IRCCS Azienda Ospedaliero-Universitaria di Bologna · Updated on 2025-01-07

500

Participants Needed

1

Research Sites

N/A

Total Duration

On this page

AI-Summary

What this Trial Is About

Researchers are investigating pulmonary thromboembolism (PTE) in cancer patients, focusing on those diagnosed either symptomatically or incidentally during cancer follow-up. The study aims to compare several scoring systems used by physicians to identify patients at low risk of serious complications within 30 days of PTE diagnosis. This could help safely discharge low-risk patients early from the emergency department, reducing lengthy hospital stays and their impact on health and psychological well-being. This observational study collects data at emergency department admission, recording information needed to calculate six different risk scores. Patients will receive usual care based on physician judgment, with no experimental treatments involved. Participants will be followed up by phone 30 days after their emergency visit to assess health status and record any major adverse events such as death, respiratory failure, or rehospitalization. The study includes both retrospective data collection and prospective enrollment over approximately three years. Participants will provide informed consent and contribute data during their emergency department visit, which takes about five minutes to collect. Follow-up phone calls last around one minute. Researchers will analyze the performance of the prognostic scores in predicting 30-day outcomes using hospital records and statistical methods. Safety monitoring focuses on identifying patients at low risk who can be discharged early without increased risk of serious complications. Overall participation lasts from initial emergency department contact through a 30-day follow-up period.

CONDITIONS

Brief Title

Pulmonary Thromboembolism in Cancer Patients: Early Rule-out From the Emergency Department

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age 18 years or older
  • Diagnosis of pulmonary embolism (symptomatic or incidental)
  • Active onco-haematological disease under oncological, haematological, or metastatic care
  • Provided informed consent to participate in the study
Not Eligible

You will not qualify if you...

  • Patients returning to the emergency department for complications related to previously diagnosed pulmonary embolism

AI-Screening

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person) at the Emergency Department

Diagnostic Evaluation

Duration - Up to initial emergency department stay

Participants diagnosed with pulmonary embolism during emergency department admission will undergo diagnostic assessments according to clinical practice.

1 to 2 visits during emergency department stay

Monitoring

Duration - 30 days

Participants will be observed for major adverse events including death, respiratory failure, or re-hospitalisation for 30 days following diagnosis.

Follow-up assessments through medical records and possible clinical visits as needed

Trial Site Locations

Total: 1 location

1

Eleonora Tubertini

Bologna, Italy, 40138

Actively Recruiting

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Research Team

E

Eleonora Tubertini, MD

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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