Actively Recruiting

Phase Not Applicable
Age: 18Years - 75Years
All Genders
NCT06828939

Pulmonary Vein Isolation With the Single Shot Endoscopic Ultra-Compliant PFA Balloon for the Treatment of AF

Led by CardioFocus · Updated on 2025-10-07

75

Participants Needed

1

Research Sites

76 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This is a prospective, single-arm First-in-Human study to demonstrate the safety and effectiveness of the CardioFocus OptiShot Pulsed Field Ablation System for catheter ablation of atrial fibrillation (AF). Patients with symptomatic paroxysmal (short-duration) AF who have not had a previous catheter ablation for AF will be considered for the study. Patients will be followed for one year after the initial ablation procedure.

CONDITIONS

Official Title

Pulmonary Vein Isolation With the Single Shot Endoscopic Ultra-Compliant PFA Balloon for the Treatment of AF

Who Can Participate

Age: 18Years - 75Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Recurrent symptomatic paroxysmal atrial fibrillation with at least one documented episode
  • Failure or intolerance of at least one antiarrhythmic drug
  • Age 18 to 75 years
  • Indicated for an ablation procedure according to guidelines or study site practice
  • Willing and able to provide informed consent and participate in baseline and follow-up assessments for the study duration
Not Eligible

You will not qualify if you...

  • Overall good health as established by multiple criteria

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Na Homolce Hospital

Prague, Czech Republic, Czechia

Actively Recruiting

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Research Team

V

Vikramaditya Mediratta, MS

CONTACT

L

Lisa Hausmann, MPH

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

TREATMENT

Number of Arms

1

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Pulmonary Vein Isolation With the Single Shot Endoscopic Ultra-Compliant PFA Balloon for the Treatment of AF | DecenTrialz