Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
NCT04109638

Pulsed Electromagnetic Field (PEMF) Therapy for Post-operative Pain Following Orthopedic Surgery

Led by Stanford University · Updated on 2026-01-21

76

Participants Needed

1

Research Sites

313 weeks

Total Duration

On this page

Sponsors

S

Stanford University

Lead Sponsor

E

Endonovo

Collaborating Sponsor

AI-Summary

What this Trial Is About

The primary objective of this study is to prospectively determine, at 10 days after orthopedic shoulder or knee surgery, if pulsed electromagnetic field (PEMF) therapy is beneficial in reducing patient-reported post-operative pain, as measured by visual analog scale (VAS). The amount of pain medication taken daily and the physical function outcome scores after surgery and PEMF treatment will also be measured.

CONDITIONS

Official Title

Pulsed Electromagnetic Field (PEMF) Therapy for Post-operative Pain Following Orthopedic Surgery

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Male or female aged 18 years or older at the time of consent
  • Scheduled for shoulder or knee surgery
  • No use of NSAIDs for one week prior to surgery (low-dose aspirin 81 mg allowed)
  • Willing and able to participate in post-operative physical therapy exercises
  • Willing to understand and sign the informed consent document
Not Eligible

You will not qualify if you...

  • Known collagen disorders such as osteogenesis imperfecta or Ehlers-Danlos syndrome
  • Known inflammatory or autoimmune connective tissue diseases including gout affecting the shoulder, scleroderma, SLE, rheumatoid disease, or calcific tendonitis of the shoulder
  • Metabolic bone diseases such as Paget's disease or osteomalacia
  • Deltoid defect, deltoid palsy, or any pseudoparalysis
  • Diabetes
  • HIV or hepatitis infection
  • Diagnosis of fibromyalgia or other chronic pain syndromes
  • Shoulder or knee pain of unknown cause
  • Active malignancy in the past 5 years or ongoing neoplastic disease except benign skin cancer
  • Use of corticosteroids (except asthma or ophthalmic medications), antineoplastic, immunostimulation, or immunosuppressive agents within 30 days before surgery
  • Septic or local/systemic infection
  • Active substance abuse or history of substance abuse not under care for over 5 years (including medical marijuana and CBD oils)
  • Consumption of more than 14 standard drinks per week for men or more than 7 for women
  • Currently seeking or receiving worker's compensation for this injury or related litigation
  • Major mental illnesses preventing protocol compliance or completing outcome measures
  • Coexisting cervical spinal pathologies such as radiculopathies or myelopathies
  • Mental or physical conditions preventing compliance with the study protocol

AI-Screening

AI-Powered Screening

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Trial Site Locations

Total: 1 location

1

Stanford University

Redwood City, California, United States, 94063

Actively Recruiting

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Research Team

M

Michelle Xiao, BS

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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