Actively Recruiting

Phase Not Applicable
Age: 25Years - 99Years
All Genders
Healthy Volunteers
NCT06744764

Pulsed Electromagnetic Fields in Preventing Physical Deconditioning in Patients Undergoing Prolonged Hospitalization

Led by National University Hospital, Singapore · Updated on 2025-01-08

76

Participants Needed

2

Research Sites

137 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The goal of this clinical trial is to examine if pulsed electromagnetic fields (PEMF) can prevent or decrease physical deconditioning associated with prolonged hospitalisation and immobility of haematology patients. The main question\[s\] it aims to answer \[is/are\]: * Does haematology patients undergoing prolonged hospitalisation have no or decreased physical deconditioning when exposed to PEMF? * What are the changes in muscle secretome at baseline and after exposure to PEMF? Researchers will compare haematology patients who receive PEMF against patients who did not receive the treatment to see if there is a change in physical deconditioning. Healthy volunteers will also be recruited and randomized to either exposure to PEMF or no exposure. Haematology patients will * Have their blood taken at baseline, 4 weeks from baseline and 8 weeks from baseline. * Undergo SPPB test at baseline, 4 weeks and 8 weeks from baseline, and the test comprises of the time up and go test, 4 minute walk test and sit to stand test. * Either expose to PEMF twice per week for 4 consecutive weeks or no exposure. Healthy volunteers will * Have their blood taken at baseline, 4 weeks from baseline and 8 weeks from baseline. * Either expose to PEMF twice per week for 4 consecutive weeks or no exposure.

CONDITIONS

Official Title

Pulsed Electromagnetic Fields in Preventing Physical Deconditioning in Patients Undergoing Prolonged Hospitalization

Who Can Participate

Age: 25Years - 99Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Haematology patients undergoing induction chemotherapy for acute leukemia
  • Haematology patients undergoing haematopoietic stem cell transplant
  • ECOG performance status 0-24 and able to walk at baseline for physical testing
  • Healthy volunteers without major diseases, not on medications, and not needing long-term medical care
Not Eligible

You will not qualify if you...

  • Patients who do not consent to participate
  • Pregnant women among healthy volunteers

AI-Screening

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Trial Site Locations

Total: 2 locations

1

NUHS Investigational Medicine Unit

Kent Ridge, Singapore, 117599

Completed

2

National University Hospital

Kent Ridge, Singapore, 119074

Actively Recruiting

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Research Team

M

Melissa Ooi, MB BCh, BAO, MRCP(I), FRCPath,

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

DOUBLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

SUPPORTIVE_CARE

Number of Arms

4

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