Actively Recruiting
The PURI-HF (Air Purifiers on Heart Failure) Trial
Led by NYU Langone Health · Updated on 2026-01-29
255
Participants Needed
3
Research Sites
216 weeks
Total Duration
On this page
Sponsors
N
NYU Langone Health
Lead Sponsor
N
National Institute of Environmental Health Sciences (NIEHS)
Collaborating Sponsor
AI-Summary
What this Trial Is About
Indoor air pollution and fine mode particulate matter with an aerodynamic diameter smaller than 2.5 micrometers (PM2.5) is a major contributor to global morbidity and mortality, particularly due to cardiovascular disease. This project aims to demonstrate the efficacy, feasibility and effectiveness of portable air filters in improving indoor PM2.5 levels and improving functional capacity of heart failure patients with reduced ejection fraction in India. The findings from the project will add to existing knowledge of innovative and scalable strategies to improve environmental and cardiovascular health worldwide. The overall objective of this study is to demonstrate the efficacy, feasibility, and effectiveness of portable air filters in improving indoor PM2.5 levels and improving functional capacity of heart failure patients with reduced ejection fraction in India.
CONDITIONS
Official Title
The PURI-HF (Air Purifiers on Heart Failure) Trial
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Adults 18 years of age or older diagnosed with heart failure with a reduced ejection fraction of 40% or less within the past six months
- New York Heart Association (NYHA) class II to IV heart failure
You will not qualify if you...
- Listed for a cardiac transplant
- History of cardiac resynchronization therapy (CRT) device implantation in the last 3 months
- Currently receiving oxygen therapy
- Severe pulmonary disease
- Unable to walk
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 3 locations
1
Centre for Chronic Disease Control (CCDC)
Thiruvananthapuram, Kerala, India
Actively Recruiting
2
All India Institute of Medical Sciences (AIIMS)
Delhi, Punjab, India
Actively Recruiting
3
Public Health Foundation of India (PHFI)
Ludhiana, Punjab, India
Actively Recruiting
Research Team
R
Rajesh Vedanthan, MD, MPH
CONTACT
J
Jessica Gjonaj
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
OTHER
Number of Arms
2
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