Actively Recruiting

Age: 18Years +
All Genders
NCT07096284

The PvCO2-PaCO2/CaO2-CvO2 Ratio in Septic Shock

Led by Avicenna Military Hospital · Updated on 2026-03-31

30

Participants Needed

3

Research Sites

77 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The ratio of the venous-arterial carbon dioxide partial pressure difference to the arteriovenous oxygen content difference (Pv-aCO₂/Ca-vO₂) may be a marker of anaerobic metabolism in patients with acute circulatory failure. This study aims to assess the prognostic value of the PvCO2-PaCO2/CaO2-CvO2 in the early phase of septic shock.

CONDITIONS

Official Title

The PvCO2-PaCO2/CaO2-CvO2 Ratio in Septic Shock

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients aged over 18 years
  • Septic shock defined by sepsis with persistent low blood pressure requiring vasopressors to keep mean arterial pressure at or above 65 mmHg
  • Blood lactate level greater than 2 mmol/L despite adequate fluid resuscitation
  • Sepsis confirmed or suspected with associated organ dysfunction such as neurological, respiratory, kidney, liver, or blood abnormalities
Not Eligible

You will not qualify if you...

  • No central venous access available
  • Central venous access not positioned in the superior vena cava (for example, femoral access)

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 3 locations

1

Avicenna Military Hospital

Marrakesh, Marrakesh, Morocco, 40000

Actively Recruiting

2

Avicenna Military Hospital

Marrakesh, Morocco, 40000

Actively Recruiting

3

Department of critical care Medicine. Avicenna Military Hospital

Marrakesh, Morocco, 40000

Actively Recruiting

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Research Team

Y

Younes Aissaoui Professor of critical care medicine

CONTACT

A

Ayoub Belhadj Professor of critical care medicine

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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