Actively Recruiting

Phase 2
Age: 18Years +
MALE
NCT04700332

PyL in Patients With High Risk and Biochemically Recurrent Prostate Cancer

Led by Hoag Memorial Hospital Presbyterian · Updated on 2021-07-27

184

Participants Needed

1

Research Sites

97 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The standard of care imaging of prostate cancer metastases recommended by the National Comprehensive Cancer Network (NCCN), CT of the chest/abdomen/pelvis and bone scan, may be suboptimal. PyL is a novel PET tracer designed to detect prostate specific membrane antigen (PSMA) expressed on prostate cancer cells. PyL PET/CT may provide improved evaluation of clinically significant metastases in patients with prostate cancer.

CONDITIONS

Official Title

PyL in Patients With High Risk and Biochemically Recurrent Prostate Cancer

Who Can Participate

Age: 18Years +
MALE

Eligibility Criteria

Eligible

You may qualify if you...

  • Male 18 years of age or older
  • Histologically confirmed adenocarcinoma of the prostate
  • Patients must meet one of the following:
    • High risk prostate cancer (PSA >10, Gleason 8-10, or clinical stage >T2c) with planned prostatectomy or radiation therapy
    • Biochemical recurrence with PSA >0.2 ng/ml after prostatectomy or ≥2 ng/ml above PSA nadir after radiotherapy, and no metastases on standard imaging within 3 months
Not Eligible

You will not qualify if you...

  • Any condition or abnormality that may compromise patient safety or data quality as judged by the investigator
  • Inability to undergo PET/CT scanning due to weight limits (over 450 pounds)
  • Change in therapy since standard of care imaging

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Hoag Memorial Hospital Presbyterian

Irvine, California, United States, 92618

Actively Recruiting

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Research Team

B

Beth Thomsen

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NON_RANDOMIZED

Model

PARALLEL

Primary Purpose

DIAGNOSTIC

Number of Arms

2

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