Actively Recruiting

Phase 3
Age: 3Years - 17Years
All Genders
Healthy Volunteers
NCT05276557

PyloPlus Urea Breath Test System Pediatric Safety and Efficacy Study

Led by ARJ Medical, Inc. · Updated on 2023-05-06

40

Participants Needed

3

Research Sites

28 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This is a multi-center, non-randomized, open label study. Subjects will be enrolled on a walk-in basis. Screening data will be reviewed to determine subject eligibility. Subjects who meet all inclusion criteria and none of the exclusion criteria will be entered into the study. All children will be exposed to non-radioactive 13C-Urea with citric acid, and shall submit a stool sample. Centers will house a PyloPlus UBT Analyzer to document results. PyloPlus Analyzer results shall remain blinded to the investigator and treating physician. No patient management decisions should be made based on the investigational PyloPlus® UBT System. Treating physician will prescribe a H. Pylori Stool Antigen Test to Stool test at either LabCorp or Quest Diagnostic, for the patient, which will be used for diagnostic purposes by the ordering physician. Total duration of study is anticipated to be approximately 6 months.

CONDITIONS

Official Title

PyloPlus Urea Breath Test System Pediatric Safety and Efficacy Study

Who Can Participate

Age: 3Years - 17Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Male or female age 3-17 at the time of visit
  • Subject or legal guardian is willing to sign the Informed Consent/Assent Form
  • No treatment for H. pylori infection in the past 4 weeks
Not Eligible

You will not qualify if you...

  • Pregnant or lactating females
  • Any condition or abnormality that could affect patient safety or data quality
  • Participation in other interventional trials
  • Allergy to test substrates
  • Antibiotic use within 4 weeks before testing
  • Consumption of mouthwash, chewing gum, carbonated drinks, cigarette smoke, acetone, alcohol, or food within 1 hour before the PyloPlus UBT test
  • Children 12 years and older excluded after one-third of sample size for this group is reached

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 3 locations

1

Dolphin Medical Research

Doral, Florida, United States, 33172

Actively Recruiting

2

Orlando Health, Inc.

Orlando, Florida, United States, 32806

Actively Recruiting

3

Harmony United Research

El Paso, Texas, United States, 79902

Actively Recruiting

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Research Team

C

Clinical Trial Manager

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

DIAGNOSTIC

Number of Arms

1

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