Actively Recruiting

Phase 3
Age: 18Years +
All Genders
Healthy Volunteers
NCT05681689

PyloPlus Urea Breath Test System Post Therapy Efficacy Confirmation Study

Led by ARJ Medical, Inc. · Updated on 2023-05-06

77

Participants Needed

2

Research Sites

23 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This is a multi-center, non-randomized, open label study. Subjects will be enrolled if they are deemed eligible given the inclusion criteria. Subjects who meet all inclusion criteria and none of the exclusion criteria will be entered into the study. Subjects will be exposed to non-radioactive 13C-Urea with citric acid, and may submit a stool sample or undergo endoscopy for Rapid Urease Test and Histology samples. Center(s) will house a PyloPlus UBT Analyzer to document results. PyloPlus Analyzer results shall remain blinded to the investigator and treating physician. No patient management decisions should be made based on the investigational PyloPlus UBT System. Treating physician will either prescribe a H. pylori Stool Antigen Test through P4 Diagnostics, along with another Urea Breath Test using Breath ID, or patient will undergo Endoscopy to provide a composite reference method consisting of Rapid Urease Test and Histology. These will act as the comparators to the PyloPlus Urea Breath Test System.

CONDITIONS

Official Title

PyloPlus Urea Breath Test System Post Therapy Efficacy Confirmation Study

Who Can Participate

Age: 18Years +
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Male or Female at least 18 years of age
  • Diagnosed with H. pylori and treated within the past 6 months
  • No treatment for H. pylori or use of proton pump inhibitors in the past 4 weeks
Not Eligible

You will not qualify if you...

  • Pregnant or lactating women
  • Any condition or abnormality that may compromise patient safety or data quality as judged by the investigator
  • Participation in other interventional trials
  • Allergy to test substrates
  • Use of antibiotics within 4 weeks before testing
  • Consumption of mouthwash, chewing gum, carbonated beverages, cigarette smoke, acetone, alcohol, or food at least 1 hour before the PyloPlus UBT test

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 2 locations

1

Dolphin Medical Research

Doral, Florida, United States, 33172

Actively Recruiting

2

Hudson County Clinical Trials Research Center

Union City, New Jersey, United States, 07087

Actively Recruiting

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Research Team

C

Clinical Trial Manager

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

DIAGNOSTIC

Number of Arms

1

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