Actively Recruiting
Led by Kayseri City Hospital · Updated on 2026-04-20
90
Participants Needed
1
Research Sites
4 weeks
Total Duration
Researchers are evaluating the use of the non-invasive Conox monitor during thyroidectomy surgery to see how it affects opioid use during the operation. The study also examines its impact on recovery time, postoperative agitation, and pain levels. Additionally, it explores how the qCON and qNOX values from this device relate to traditional heart rate and blood pressure measurements. Participants receive anesthesia induction with propofol, fentanyl, and rocuronium, followed by maintenance with sevoflurane and remifentanil. In the Conox group, anesthesia depth and pain response are guided by EEG-based qCON and qNOX values to adjust drug dosing. The control group follows standard care using heart rate and blood pressure to guide opioid use. Measurements include opioid consumption, recovery times, agitation, and pain scores. During the study, participants will have opioid use and recovery monitored closely, including pain assessments every five minutes in the post-anesthesia care unit. Researchers will also record extubation times and agitation scores. The study aims to compare clinical outcomes between groups and assess correlations between EEG monitoring and traditional hemodynamic parameters, with the overall goal of improving anesthesia management in thyroid surgery.
CONDITIONS
qCON/qNOX-Guided Anesthesia in Patients Undergoing Thyroidectomy Surgery
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Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
Duration - Day of surgery
Participants undergo thyroidectomy surgery with anesthesia management guided either by the Conox EEG monitor or standard clinical monitoring. Anesthetic and opioid doses are adjusted during surgery to optimize anesthesia depth and pain management.
1 surgical visit (in-person)
Duration - Within the first 30 minutes after surgery
After surgery, participants are monitored in the post-anesthesia care unit (PACU) where pain scores and recovery parameters are assessed frequently to evaluate comfort and recovery quality.
Assessments every 5 minutes in PACU
Total: 1 location
1
Kayseri City Hospital
Kayseri, Kayseri, Turkey (Türkiye), 38080
Actively Recruiting
Ç
Çiğdem Ünal Kantekin, MD
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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Connie Mun-Price, Kathleen Than, Margaret J Klein...
https://pubmed.ncbi.nlm.nih.gov/35699795