Studying the Use of qCONqNOX-Guided Anesthesia with the Conox Monitor to Improve Outcomes in Thyroid Surgery Patients
Led by Kayseri City Hospital · Updated on 2026-04-20
90
Participants Needed
1
Research Sites
4 weeks
Total Duration
AI-Summary
What this Trial Is About
Researchers are evaluating the use of the non-invasive Conox monitor during thyroidectomy surgery to see how it affects opioid use during the operation. The study also examines its impact on recovery time, postoperative agitation, and pain levels. Additionally, it explores how the qCON and qNOX values from this device relate to traditional heart rate and blood pressure measurements.
Participants receive anesthesia induction with propofol, fentanyl, and rocuronium, followed by maintenance with sevoflurane and remifentanil. In the Conox group, anesthesia depth and pain response are guided by EEG-based qCON and qNOX values to adjust drug dosing. The control group follows standard care using heart rate and blood pressure to guide opioid use. Measurements include opioid consumption, recovery times, agitation, and pain scores.
During the study, participants will have opioid use and recovery monitored closely, including pain assessments every five minutes in the post-anesthesia care unit. Researchers will also record extubation times and agitation scores. The study aims to compare clinical outcomes between groups and assess correlations between EEG monitoring and traditional hemodynamic parameters, with the overall goal of improving anesthesia management in thyroid surgery.
CONDITIONS
Brief Title
qCON/qNOX-Guided Anesthesia in Patients Undergoing Thyroidectomy Surgery
Research Team
Ç
Çiğdem Ünal Kantekin, MD
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Thyroidectomy patients with ASA physical status I or II
Patients who have provided written informed consent
You will not qualify if you...
Skin lesions preventing EEG electrode placement
Presence of neurological disorders such as epilepsy
Anticipated difficult airway during anesthesia
Your Study Journey
Screening
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
Surgery and Immediate Post-operative Care
Duration - Day of surgery
Participants undergo thyroidectomy surgery with anesthesia management guided either by the Conox EEG monitor or standard clinical monitoring. Anesthetic and opioid doses are adjusted during surgery to optimize anesthesia depth and pain management.
1 surgical visit (in-person)
Post-operative Follow-up
Duration - Within the first 30 minutes after surgery
After surgery, participants are monitored in the post-anesthesia care unit (PACU) where pain scores and recovery parameters are assessed frequently to evaluate comfort and recovery quality.
Assessments every 5 minutes in PACU
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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Studying the Use of qCONqNOX-Guided Anesthesia with the Conox Monitor to Improve Outcomes in Thyroid Surgery Patients
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Published Research Related To This Trial
The effect of anesthesia without opioid on perioperative opioid demand in children with severe obstructive sleep apnea (OSA) for adenotonsillectomies - single-center retrospective observational study.
Connie Mun-Price, Kathleen Than, Margaret J Klein...